Synthesis, characterization and microbiocidal studies of novel ionic liquid tagged Schiff bases

被引：24
作者：
Khungar, Bharti [1 ]
Rao, Madharam Sudershan [1 ]
Pericherla, Kasiviswanadharaju [1 ]
Nehra, Pankaj [1 ]
Jain, Navin [2 ]
Panwar, Jitendra [2 ]
Kumar, Anil [1 ]
机构：
[1] Birla Inst Technol & Sci, Dept Chem, Pilani 333031, Rajasthan, India
[2] Birla Inst Technol & Sci, Dept Biol Sci, Pilani 333031, Rajasthan, India
来源：
COMPTES RENDUS CHIMIE | 2012年 / 15卷 / 08期
关键词：
Ionic liquid; Functionalized ionic liquid; Schiff base; Antibacterial; Antifungal; ANTIMICROBIAL ACTIVITIES; EXTRACTION; SOLVENTS;
D O I：
10.1016/j.crci.2012.05.023
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of novel imidazolium ionic liquid, tagged Schiff, has been described. The synthesis was achieved in three steps from 2,4-dihydroxybenzaldehyde by selective Aviation with 1,3-dibromopropane, followed by reaction with 1-methylimidazole and Schiff base formation with aromatic amines. The compounds were evaluated for antibacterial and antifungal activities. The ionic liquid tagged Schiff base 4a showed the inhibition of both Gram positive and Gram negative bacteria. It also showed broad spectrum antifungal activity against all four tested fungi; however, 4f showed highest antifungal activity against A. niger. (C) 2012 Published by Elsevier Masson SAS on behalf of Academie des sciences.
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收藏
页码：669 / 674
页数：6
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