Biologically Responsive Polymeric Nanoparticles for Drug Delivery

被引：180
|
作者：
Colson, Yolonda L. [1 ]
Grinstaff, Mark W. [2 ,3 ]
机构：
[1] Brigham & Womens Hosp, Dept Surg, Div Thorac Surg, Boston, MA 02215 USA
[2] Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA
[3] Boston Univ, Dept Chem, Boston, MA 02215 USA
来源：
ADVANCED MATERIALS | 2012年 / 24卷 / 28期
基金：
美国国家科学基金会;
关键词：
responsive system; triggered drug delivery; nanoparticles; pH; oxidation; POLY(BETA-AMINO ESTER) NANOPARTICLES; TUMOR-TARGETED DELIVERY; PH-SENSITIVE SYSTEM; LOADED EXPANSILE NANOPARTICLES; IN-VIVO; HYDROPHOBIC DRUGS; LYMPH-NODES; PACLITAXEL; PARTICLES; DEGRADATION;
D O I：
10.1002/adma.201200420
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.
引用
收藏
页码：3878 / 3886
页数：9
相关论文
共 50 条
  • [1] Stimuli responsive polymeric nanoparticles in regulated drug delivery for cancer
    Yadav, Deepak
    Suri, Suruchi
    Chaudhary, Anis A.
    Hemant
    Beg, Mohd N.
    Garg, Veena
    Asif, Mohd
    Ahmad, Altaf
    POLISH JOURNAL OF CHEMICAL TECHNOLOGY, 2012, 14 (01) : 57 - 64
  • [2] Stimuli-Responsive Polymeric Nanoparticles for Nanomedicine
    Crucho, Carina I. C.
    CHEMMEDCHEM, 2015, 10 (01) : 24 - 38
  • [3] Polymeric nanoparticles responsive to intracellular ROS for anticancer drug delivery
    Xu, Long
    Zhao, Mingying
    Gao, Wenxia
    Yang, Yidi
    Zhang, Jianfeng
    Pu, Yuji
    He, Bin
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 181 : 252 - 260
  • [4] Capsules with responsive polymeric shells for applications beyond drug delivery
    Wang, Yifei
    Starvaggi, Nicholas
    Pentzer, Emily
    POLYMER CHEMISTRY, 2023, 14 (35) : 4033 - 4047
  • [5] Environment-responsive Polymeric Nanoparticles as Drug Delivery Systems for Cancer Therapy
    Yang Yang
    She Wen-Chuan
    Luo Kui
    Gu Zhong-Wei
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2013, 40 (10) : 1039 - 1048
  • [6] Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery
    Thambi, Thavasyappan
    Deepagan, V. G.
    Yoon, Hong Yeol
    Han, Hwa Seung
    Kim, Seol-Hee
    Son, Soyoung
    Jo, Dong-Gyu
    Ahn, Cheol-Hee
    Suh, Yung Doug
    Kim, Kwangmeyung
    Kwon, Ick Chan
    Lee, Doo Sung
    Park, Jae Hyung
    BIOMATERIALS, 2014, 35 (05) : 1735 - 1743
  • [7] pH-Responsive Nanoparticles for Drug Delivery
    Gao, Weiwei
    Chan, Juliana M.
    Farokhzad, Omid C.
    MOLECULAR PHARMACEUTICS, 2010, 7 (06) : 1913 - 1920
  • [8] Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery
    Cheng, Ru
    Meng, Fenghua
    Deng, Chao
    Klok, Harm-Anton
    Zhong, Zhiyuan
    BIOMATERIALS, 2013, 34 (14) : 3647 - 3657
  • [9] Use of stimulatory responsive soft nanoparticles for in drug delivery
    Hughes, Krystal A.
    Misra, Bishal
    Maghareh, Maryam
    Bobbala, Sharan
    NANO RESEARCH, 2023, 16 (05) : 6974 - 6990
  • [10] Polymeric Nanoparticles for Drug Delivery in Osteoarthritis
    Pontes, Adriano P.
    Welting, Tim J. M.
    Rip, Jaap
    Creemers, Laura B.
    PHARMACEUTICS, 2022, 14 (12)
12345