Therapeutic Potential of Essential Oils Focusing on Diterpenes

被引:67
作者
Torequl Islam, Md. [1 ,2 ,3 ]
Oliveira Ferreira da Mata, Ana Maria [2 ]
Sousa de Aguiar, Rai Pablo [2 ]
Correia Jardim Paz, Marcia Fernanda [1 ,2 ]
Oliveira Barros de Alencar, Marcus Vincius [1 ,2 ]
Pinheiro Ferreira, Paulo Michel [1 ,2 ,4 ]
de Carvalho Melo-Cavalcante, Ana Amelia [1 ,2 ]
机构
[1] Univ Fed Piaui, Postgrad Program Biotechnol, Northeast Biotechnol Network RENORBIO, BR-64049550 Teresina, Brazil
[2] Univ Fed Piaui, Postgrad Program Pharmaceut Sci, BR-64049550 Teresina, Brazil
[3] Southern Univ Bangladesh, Dept Pharm, 22 Shahid Mirza Lane E,Acad Bldg 2,1st Floor, Mehedibag 4000, Chittagong, Bangladesh
[4] Univ Fed Piaui, Dept Physiol & Biophys, BR-64049550 Teresina, Brazil
关键词
diterpenes; essential oils; drug source; plant-derived; phytotherapy; LABDANE-TYPE DITERPENES; INDUCED NO PRODUCTION; CASSANE-TYPE DITERPENES; LEAF ESSENTIAL OIL; CANCER-CELL LINES; TEA TREE OIL; NF-KAPPA-B; IN-VITRO; CLERODANE DITERPENES; NEOCLERODANE DITERPENES;
D O I
10.1002/ptr.5652
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Among all plant derivates, essential oils (EOs) have gained the attention of many scientists. Diterpenes, a family of components present in some EO, are becoming a milestone in the EOs world. The goal of this review is to describe a scenario of diterpenes taking into health-consumption deportment. Previous studies revealed that diterpenes have antioxidant, antimicrobial, antiviral, antiprotozoal, cytotoxic, anticancer, antigenotoxic, antimutagenic, chemopreventive, antiinflammatory, antinociceptive, immunostimulatory, organoprotective, antidiabetic, lipid-lowering, antiallergic, antiplatelet, antithrombotic, and antitoxin activities. In conclusion, diterpenes may be an immense featuring concern in pharmaceutical consumption from a drug discovery point of view. Copyright (C) 2016 John Wiley & Sons, Ltd.
引用
收藏
页码:1420 / 1444
页数:25
相关论文
共 229 条
[91]   Genotoxicity and antigenotoxicity of Origanum oil and carvacrol evaluated by Ames Salmonella/microsomal test [J].
Ipek, E ;
Zeytinoglu, H ;
Okay, S ;
Tuylu, BA ;
Kurkcuoglu, M ;
Baser, KHC .
FOOD CHEMISTRY, 2005, 93 (03) :551-556
[92]  
Islam M. T., 2016, Int. Arch. Med, DOI [10.3823/1941, DOI 10.3823/1941]
[93]   Diterpenes: Advances in Neurobiological Drug Research [J].
Islam, Md. Torequl ;
da Silva, Claucenira Bandeira ;
Oliveira Barros de Alencar, Marcus Vinicius ;
Correia Jardim Paz, Marcia Fernanda ;
de Castro Almeida, Fernanda Regina ;
de Carvalho Melo-Cavalcante, Ana Amelia .
PHYTOTHERAPY RESEARCH, 2016, 30 (06) :915-928
[94]   Phytol in a pharma-medico-stance [J].
Islam, Md Torequl ;
Oliveira Barros de Alencar, Marcus Vinicius ;
Machado, Katia da Conceicao ;
Machado, Keylla da Conceicao ;
de Carvalho Melo-Cavalcante, Ana Amelia ;
de Sousa, Damiao Pergentino ;
de Freitas, Rivelilson Mendes .
CHEMICO-BIOLOGICAL INTERACTIONS, 2015, 240 :60-73
[95]   A Critical Approach to Evaluating Clinical Efficacy, Adverse Events and Drug Interactions of Herbal Remedies [J].
Izzo, Angelo A. ;
Hoon-Kim, Sung ;
Radhakrishnan, Rajan ;
Williamson, Elizabeth M. .
PHYTOTHERAPY RESEARCH, 2016, 30 (05) :691-700
[96]   Antimutagenic Potential and Modulation of Carcinogen-Metabolizing Enzymes by Ginger Essential Oil [J].
Jeena, Kottarapat ;
Liju, Vijayasteltar B. ;
Viswanathan, Ramanath ;
Kuttan, Ramadasan .
PHYTOTHERAPY RESEARCH, 2014, 28 (06) :849-855
[97]   Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures [J].
Jiao, Wei ;
Dong, Weiwei ;
Li, Zhefeng ;
Deng, Meicai ;
Lu, Runhua .
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (13) :4786-4792
[98]   Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity [J].
Jimenez-Romero, Carlos ;
Mayer, Alejandro M. S. ;
Rodriguez, Abimael D. .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (01) :344-348
[99]   Relevance of the carnosic acid/carnosol ratio for the level of rosemary diterpene transfer and for improving lamb meat antioxidant status [J].
Jordan, Maria J. ;
Castillo, Julian ;
Banon, Sancho ;
Martinez-Conesa, Cristina ;
Sotomayor, Jose A. .
FOOD CHEMISTRY, 2014, 151 :212-218
[100]   Inhibitory Effects and Molecular Mechanism of Dieckol Isolated from Marine Brown Alga on COX-2 and iNOS in Microglial Cells [J].
Jung, Won-Kyo ;
Heo, Soo-Jin ;
Jeon, You-Jin ;
Lee, Chang-Min ;
Park, Yeong-Min ;
Byun, Hee-Guk ;
Choi, Yung Hyun ;
Park, Sae-Gwang ;
Choi, Il-Whan .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (10) :4439-4446