Therapeutic Potential of Essential Oils Focusing on Diterpenes

被引:67
作者
Torequl Islam, Md. [1 ,2 ,3 ]
Oliveira Ferreira da Mata, Ana Maria [2 ]
Sousa de Aguiar, Rai Pablo [2 ]
Correia Jardim Paz, Marcia Fernanda [1 ,2 ]
Oliveira Barros de Alencar, Marcus Vincius [1 ,2 ]
Pinheiro Ferreira, Paulo Michel [1 ,2 ,4 ]
de Carvalho Melo-Cavalcante, Ana Amelia [1 ,2 ]
机构
[1] Univ Fed Piaui, Postgrad Program Biotechnol, Northeast Biotechnol Network RENORBIO, BR-64049550 Teresina, Brazil
[2] Univ Fed Piaui, Postgrad Program Pharmaceut Sci, BR-64049550 Teresina, Brazil
[3] Southern Univ Bangladesh, Dept Pharm, 22 Shahid Mirza Lane E,Acad Bldg 2,1st Floor, Mehedibag 4000, Chittagong, Bangladesh
[4] Univ Fed Piaui, Dept Physiol & Biophys, BR-64049550 Teresina, Brazil
关键词
diterpenes; essential oils; drug source; plant-derived; phytotherapy; LABDANE-TYPE DITERPENES; INDUCED NO PRODUCTION; CASSANE-TYPE DITERPENES; LEAF ESSENTIAL OIL; CANCER-CELL LINES; TEA TREE OIL; NF-KAPPA-B; IN-VITRO; CLERODANE DITERPENES; NEOCLERODANE DITERPENES;
D O I
10.1002/ptr.5652
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Among all plant derivates, essential oils (EOs) have gained the attention of many scientists. Diterpenes, a family of components present in some EO, are becoming a milestone in the EOs world. The goal of this review is to describe a scenario of diterpenes taking into health-consumption deportment. Previous studies revealed that diterpenes have antioxidant, antimicrobial, antiviral, antiprotozoal, cytotoxic, anticancer, antigenotoxic, antimutagenic, chemopreventive, antiinflammatory, antinociceptive, immunostimulatory, organoprotective, antidiabetic, lipid-lowering, antiallergic, antiplatelet, antithrombotic, and antitoxin activities. In conclusion, diterpenes may be an immense featuring concern in pharmaceutical consumption from a drug discovery point of view. Copyright (C) 2016 John Wiley & Sons, Ltd.
引用
收藏
页码:1420 / 1444
页数:25
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