Ytterbium-Based Bioprobes for Near-Infrared Two-Photon Scanning Laser Microscopy Imaging

被引：131

作者：

D'Aleo, Anthony ^{[1
]}

Bourdolle, Adrien ^{[1
]}

Brustlein, Sophie ^{[2
]}

Fauquier, Teddy ^{[4
]}

Grichine, Alexei ^{[3
]}

Duperray, Alain ^{[3
]}

Baldeck, Patrice L. ^{[1
]}

Andraud, Chantal ^{[1
]}

Brasselet, Sophie ^{[2
]}

Maury, Olivier ^{[1
]}

机构：

[1] Univ Lyon 1, ENS Lyon, CNRS, UMR 5182, F-69364 Lyon, France

[2] Univ Aix Marseille 3, Inst Fresnel, CNRS, Ecole Cent Marseille, F-13397 Marseille 20, France

[3] Univ Grenoble 1, Inst Albert Bonniot, INSERM, CHU Grenoble,EFS,U823, F-38042 Grenoble, France

[4] Univ Lyon, Inst Genom Fonct Lyon, CNRS, INRA,Ecole Normale Super Lyon, F-69364 Lyon, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 27期

关键词：

bioimaging; biphotonic microscopy; lanthanide complexes; ytterbium; LANTHANIDE COMPLEXES; EFFICIENT SENSITIZATION; MULTIPHOTON MICROSCOPY; EUROPIUM COMPLEXES; LUMINESCENCE; LIGANDS; PROBES; IONS;

D O I：

10.1002/anie.201202212

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cleanly separated by two photons: The design and photophysical characterization of a new highly stable macrocyclic ytterbium complex featuring a two-photon antenna ligand is described (see picture). The biphotonic sensitization of the near-infrared ytterbium(III) luminescence and the conception of an unconventional near-infrared biphotonic microscope allow performing in-depth imaging of thick tissues. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6622 / 6625

页数：4

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