When mastectomy becomes inevitable: The nipple-sparing approach

被引:71
作者
Petit, JY
Veronesi, U
Luini, A
Orecchia, R
Rey, PC
Martella, S
Didier, F
De Lorenzi, F
Rietjens, M
Garusi, C
Sonzogni, A
Galimberti, V
Leida, E
Lazzari, R
Giraldo, A
机构
[1] European Inst Oncol, Dept Plast Surg, I-20141 Milan, Italy
[2] European Inst Oncol, Senol Dept, I-20141 Milan, Italy
[3] European Inst Oncol, Dept Radiotherapy, I-20141 Milan, Italy
[4] European Inst Oncol, Psychooncol Unit, I-20141 Milan, Italy
[5] European Inst Oncol, Dept Pathol, I-20141 Milan, Italy
关键词
mastectomy; nipple sparing; breast cancer; intraoperative radiotherapy; IMMEDIATE BREAST RECONSTRUCTION; LOCAL RECURRENCE; AREOLA COMPLEX; SKIN; INVOLVEMENT; CANCER; IORT;
D O I
10.1016/j.breast.2005.08.028
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The preservation of the nipple areola complex (NAC) could improve the quality of life in cases of mastectomy. A novel radiosurgical. treatment combining subcutaneous mastectomy with intraoperative radiotherapy is proposed. Three hundred nipple-sparing mastectomies (NSM) were performed. Invasive (58%) and in situ (42%) carcinomas were included. Clinical complications, aesthetic results, oncological. and psychological results were recorded. The NAC necrosed totally in 10 cases and partially in 29 and it was removed in 12. Nine infections (3%) were observed and 10 prostheses removed. Good results were rated by 82.3% of the patients and by 84.8% of the surgeons. In 7.5% a radiodystrophy was observed. The sensitivity of the NAC recovered partially in 48%. Two local recurrences occurred outside the radiated field. Overall, we observed three metastases and no deaths. Sixty-eight of the patients were satisfied with their reconstructed breast and 85.5% were satisfied having preserved the NAC. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:527 / 531
页数:5
相关论文
共 29 条
[1]  
Battle J. A., 1999, CURRENT CLIN ONCOLOG, P521
[2]   Incidence of the superficial fascia and its relevance in skin-sparing mastectomy [J].
Beer, GM ;
Varga, Z ;
Budi, S ;
Seifert, B ;
Meyer, VE .
CANCER, 2002, 94 (06) :1619-1625
[3]   Touch sensibility in the breast after subcutaneous mastectomy and immediate reconstruction with a prosthesis [J].
Benediktsson, KP ;
Perbeck, L ;
Geigant, E ;
Solders, G .
BRITISH JOURNAL OF PLASTIC SURGERY, 1997, 50 (06) :443-449
[4]   Skin-sparing mastectomy - Oncologic and reconstructive considerations [J].
Carlson, GW ;
Bostwick, J ;
Styblo, TM ;
Moore, B ;
Bried, JT ;
Murray, DR ;
Wood, WC .
ANNALS OF SURGERY, 1997, 225 (05) :570-575
[5]   Local recurrence after skin-sparing mastectomy: Tumor biology or surgical conservatism? [J].
Carlson, GW ;
Styblo, TM ;
Lyles, RH ;
Bostwick, J ;
Murray, DR ;
Staley, CA ;
Wood, WC .
ANNALS OF SURGICAL ONCOLOGY, 2003, 10 (02) :108-112
[6]   Results ed immediate breast reconstruction after skin-sparing mastectomy [J].
Carlson, GW ;
Losken, A ;
Moore, B ;
Thornton, J ;
Elliott, M ;
Bolitho, G ;
Denson, DD .
ANNALS OF PLASTIC SURGERY, 2001, 46 (03) :222-228
[7]   Nipple-sparing mastectomy in breast cancer: a viable option? [J].
Cense, HA ;
Rutgers, EJT ;
Cardozo, ML ;
Van Lanschot, JJB .
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 2001, 27 (06) :521-526
[8]  
Chagpar AB, 2004, AM SURGEON, V70, P425
[9]   Nipple-sparing mastectomy - Technique and results of 54 procedures [J].
Crowe, JP ;
Kim, JA ;
Yetman, R ;
Banbury, J ;
Patrick, RJ ;
Baynes, D .
ARCHIVES OF SURGERY, 2004, 139 (02) :148-150
[10]  
Dubois JB, 1997, FRONT RADIAT THER ON, V31, P131