Hong Kong Consensus Statements for the Management of Unresectable Hepatocellular Carcinoma

被引:29
作者
Cheung, Tan-To [1 ]
Kwok, Philip Chong-Hei [2 ]
Chan, Stephen [3 ]
Cheung, Chin-Cheung [4 ]
Lee, Ann-Shing [5 ]
Lee, Victor [6 ]
Cheng, Hoi-Ching [7 ]
Nam-Hung Chia [8 ]
Chong, Charing C. N. [9 ]
Lai, Tak-Wing [10 ]
Law, Ada L. Y. [11 ]
Luk, Mai-Yee [6 ]
Tong, Chi Chung [6 ]
Yau, Thomas C. C. [12 ]
机构
[1] Univ Hong Kong, Queen Mary Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China
[2] Queen Elizabeth Hosp, Dept Radiol & Imaging, Hong Kong, Hong Kong, Peoples R China
[3] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Clin Oncol, Hong Kong, Hong Kong, Peoples R China
[4] Tuen Mun Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China
[5] Tuen Mun Hosp, Dept Clin Oncol, Hong Kong, Hong Kong, Peoples R China
[6] Univ Hong Kong, Queen Mary Hosp, Dept Clin Oncol, Hong Kong, Hong Kong, Peoples R China
[7] Queen Elizabeth Hosp, Dept Clin Oncol, Hong Kong, Hong Kong, Peoples R China
[8] Queen Elizabeth Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China
[9] Chinese Univ Hong Kong, Dept Surg, Hong Kong, Hong Kong, Peoples R China
[10] Princess Margaret Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China
[11] Pamela Youde Nethersole Eastern Hosp, Clin Oncol, Hong Kong, Hong Kong, Peoples R China
[12] Univ Hong Kong, Queen Mary Hosp, Dept Med & Surg, Hong Kong, Hong Kong, Peoples R China
关键词
Consensus; Hepatocellular carcinoma; Unresectable HCC; Hong Kong; RANDOMIZED CONTROLLED-TRIAL; SELECTIVE INTERNAL RADIATION; PORTAL-VEIN EMBOLIZATION; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; STEREOTACTIC BODY RADIOTHERAPY; MICROWAVE COAGULATION THERAPY; FOCUSED ULTRASOUND ABLATION; CANCER STAGING SYSTEM; RADIOFREQUENCY ABLATION; PHASE-III;
D O I
10.1159/000485984
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Hepatocellular carcinoma (HCC) is highly prevalent in Hong Kong due to the high prevalence of chronic hepatitis B infection. Liver cancer is the fourth most common cancer and the third most common cause of cancer death. Due to the high case load, there is a high level of local expertise in treating HCC, and the full spectrum of treatment modalities is available. This document summarizes how these modalities should be used based on the latest evidence. Summary: In 2 meetings held in early 2017, a multidisciplinary group of Hong Kong clinicians, including liver surgeons, interventional radiologists, clinical oncologists, and medical oncologists, met to update local consensus statements for management of HCC. These statements are based on the latest evidence and give detailed guidance on how to deploy these modalities, in particular for cases of HCC which are not suited to surgical resection. Key Messages: These statements give detailed information on how to decide if a patient is a candidate for resection, methods to improve candidacy for resection, and guidance for use of various nonsurgical interventions to manage patients ineligible for resection. (c) 2018 S. Karger AG, Basel
引用
收藏
页码:40 / 54
页数:15
相关论文
共 95 条
  • [91] Development of Hong Kong Liver Cancer Staging System With Treatment Stratification for Patients With Hepatocellular Carcinoma
    Yau, Thomas
    Tang, Vikki Y. F.
    Yao, Tzy-Jyun
    Fan, Sheung-Tat
    Lo, Chung-Mau
    Poon, Ronnie T. P.
    [J]. GASTROENTEROLOGY, 2014, 146 (07) : 1691 - +
  • [92] A randomized phase III study of doxorubicin versus cisplatin/interferon α-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma
    Yeo, W
    Mok, TS
    Zee, B
    Leung, TWT
    Lai, PBS
    Lau, WY
    Koh, J
    Mo, FKF
    Yu, SCH
    T Chan, A
    Hui, P
    Ma, B
    Lam, KC
    Ho, WM
    Wong, HT
    Tang, A
    Johnson, PJ
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (20): : 1532 - 1538
  • [93] Consensus on Stereotactic Body Radiation Therapy for Small-Sized Hepatocellular Carcinoma at the 7th Asia-Pacific Primary Liver Cancer Expert Meeting
    Zeng, Zhao-Chong
    Seong, Jinsil
    Yoon, Sang Min
    Cheng, Jason Chia-Hsien
    Lam, Ka-On
    Lee, Ann-Shing
    Law, Ada
    Zhang, Jian-Ying
    Hu, Yong
    [J]. LIVER CANCER, 2017, 6 (04) : 264 - 274
  • [94] Upregulation of Circulating PD-L1/PD-1 Is Associated with Poor Post-Cryoablation Prognosis in Patients with HBV-Related Hepatocellular Carcinoma
    Zeng, Zhen
    Shi, Feng
    Zhou, Lin
    Zhang, Min-Na
    Chen, Yan
    Chang, Xiu-Juan
    Lu, Yin-Ying
    Bai, Wen-Lin
    Qu, Jian-Hui
    Wang, Chun-Ping
    Wang, Hong
    Lou, Min
    Wang, Fu-Sheng
    Lv, Ji-Yun
    Yang, Yong-Ping
    [J]. PLOS ONE, 2011, 6 (09):
  • [95] Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region
    Zhu, Ran Xu
    Seto, Wai-Kay
    Lai, Ching-Lung
    Yuen, Man-Fung
    [J]. GUT AND LIVER, 2016, 10 (03) : 332 - 339