Effect of Nucleic Acid Amplification Testing on Population-Based Incidence Rates of Clostridium difficile Infection

被引:85
作者
Gould, Carolyn V. [1 ]
Edwards, Jonathan R. [1 ]
Cohen, Jessica [1 ]
Bamberg, Wendy M. [2 ]
Clark, Leigh Ann [3 ]
Farley, Monica M. [3 ,4 ,5 ]
Johnston, Helen [2 ]
Nadle, Joelle [6 ]
Winston, Lisa [7 ]
Gerding, Dale N. [8 ,9 ]
McDonald, L. Clifford [1 ]
Lessa, Fernanda C. [1 ]
机构
[1] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA
[2] Colorado Dept Hlth, Denver, CO 80220 USA
[3] Georgia Emerging Infect Program, Atlanta, GA USA
[4] Emory Univ, Div Infect Dis, Atlanta, GA 30322 USA
[5] Atlanta VA Med Ctr, Atlanta, GA USA
[6] Calif Emerging Infect Program, Oakland, CA USA
[7] Univ Calif San Francisco, Div Infect Dis, San Francisco, CA 94143 USA
[8] Hines VA Hosp, Maywood, IL USA
[9] Loyola Univ Chicago, Stritch Sch Med, Maywood, IL USA
关键词
Clostridium difficile; clinical laboratory techniques; nucleic acid amplification techniques; incidence; surveillance; REAL-TIME PCR; ENZYME-IMMUNOASSAY; DIAGNOSIS; IMPACT; TOXIN; ASSAY;
D O I
10.1093/cid/cit492
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Nucleic acid amplification testing (NAAT) is increasingly being adopted for diagnosis of Clostridium difficile infection (CDI). Data from 3 states conducting population-based CDI surveillance showed increases ranging from 43% to 67% in CDI incidence attributable to changing from toxin enzyme immunoassays to NAAT. CDI surveillance requires adjustment for testing methods.
引用
收藏
页码:1304 / 1307
页数:4
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