Treatment of hemimandibular paresthesia in a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) by combining surgical resection and PRGF-Endoret

被引：25

作者：

Anitua, E.

Begona, L. ^{[1
]}

Orive, G. ^{[1
]}

机构：

[1] Biotechnol Inst BTI, Vitoria, Spain

来源：

BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY | 2013年 / 51卷 / 08期

关键词：

BRONJ; Osteonecrosis; Bisphosphonates; PRGF; Platelet rich plasma; Paresthesia; UPDATE;

D O I：

10.1016/j.bjoms.2012.08.018

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

We report a case of a 50-year-old patient with bisphosphonate-related osteonecrosis of the jaws (BRONJs) whose symptoms included severe pain and hemimandibular paraesthesia. The treatment included resection of necrotic bone and the application of plasma rich in growth factors (PRGF (R)-Endoret (R)). We closed the ulcer in the soft tissue and her pain and paraesthesia improved. One year postoperatively sensitivity was totally recovered, pain was absent and bone was partially regenerated. (C) 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

引用

页码：E272 / E274

页数：3

共 10 条

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[2]

European Medicines Agency (EMEA). Committee for Medicinal Products for Human Use (CHMP), EMEACHMP2911252009

[3] Effect of platelet rich plasma and fibrin sealant on facial nerve regeneration in a rat model [J].