Treatment of hemimandibular paresthesia in a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) by combining surgical resection and PRGF-Endoret

被引：25
作者：
Anitua, E.
Begona, L. [1 ]
Orive, G. [1 ]
机构：
[1] Biotechnol Inst BTI, Vitoria, Spain
来源：
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY | 2013年 / 51卷 / 08期
关键词：
BRONJ; Osteonecrosis; Bisphosphonates; PRGF; Platelet rich plasma; Paresthesia; UPDATE;
D O I：
10.1016/j.bjoms.2012.08.018
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
We report a case of a 50-year-old patient with bisphosphonate-related osteonecrosis of the jaws (BRONJs) whose symptoms included severe pain and hemimandibular paraesthesia. The treatment included resection of necrotic bone and the application of plasma rich in growth factors (PRGF (R)-Endoret (R)). We closed the ulcer in the soft tissue and her pain and paraesthesia improved. One year postoperatively sensitivity was totally recovered, pain was absent and bone was partially regenerated. (C) 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：E272 / E274
页数：3
相关论文
共 10 条
  • [1] Anitua Eduardo, 2009, Clin Implant Dent Relat Res, V11 Suppl 1, pe23, DOI 10.1111/j.1708-8208.2009.00159.x
  • [2] European Medicines Agency (EMEA). Committee for Medicinal Products for Human Use (CHMP), EMEACHMP2911252009
  • [3] Effect of platelet rich plasma and fibrin sealant on facial nerve regeneration in a rat model
    Farrag, Tarik Y.
    Lehar, Mohamed
    Verhaegen, Pauline
    Carson, Kathryn A.
    Byrne, Patrick J.
    [J]. LARYNGOSCOPE, 2007, 117 (01) : 157 - 165
  • [4] Evidence Supporting the Use of Hyperbaric Oxygen in the Treatment of Osteoradionecrosis of the Jaw
    Freiberger, John J.
    Feldmeier, John J.
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2010, 68 (08) : 1903 - 1906
  • [5] Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic
    Marx, RE
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2003, 61 (09) : 1115 - 1117
  • [6] Platelet-rich therapies in the treatment of intravenous bisphosphonate-related osteonecrosis of the jaw: A report of 32 cases
    Mozzati, Marco
    Gallesio, Giorgia
    Arata, Valentina
    Pol, Renato
    Scoletta, Matteo
    [J]. ORAL ONCOLOGY, 2012, 48 (05) : 469 - 474
  • [7] Osteonecrosis of the Jaw: An Update and Review of Recommendations
    Novince, Chad M.
    Ward, Brent B.
    McCauley, Laurie K.
    [J]. CELLS TISSUES ORGANS, 2009, 189 (1-4) : 275 - 283
  • [8] The Role of Inferior Alveolar Nerve Involvement in Bisphosphonate-Related Osteonecrosis of the Jaw
    Otto, Sven
    Hafner, Sigurd
    Groetz, Knut A.
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2009, 67 (03) : 589 - 592
  • [9] American Association of Oral and Maxillofacial Surgeons Position Paper on Bisphosphonate-Related Osteonecrosis of the Jaws-2009 Update
    Ruggiero, Salvatore L.
    Dodson, Thomas B.
    Assael, Leon A.
    Landesberg, Regina
    Marx, Robert E.
    Mehrotra, Bhoomi
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2009, 67 (05) : 2 - 12
  • [10] Platelet-Rich Plasma: A Promising Product for Treatment of Peripheral Nerve Regeneration After Nerve Injury
    Yu, WenJun
    Wang, Jian
    Yin, Jun
    [J]. INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2011, 121 (04) : 176 - 180
1