Synthesis and characterization of novel biocompatible nanocapsules encapsulated lily fragrance

被引:15
作者
Ji, Weihong [1 ,2 ]
Zhang, Tianlu [1 ]
Lu, Zhiguo [1 ,2 ]
Shen, Jie [1 ,2 ]
Xiao, Zuobing [3 ,4 ]
Zhang, Xin [1 ]
机构
[1] Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] Shanghai Res Inst Fragrance & Flavor Ind, Shanghai 200232, Peoples R China
[4] Shanghai Inst Technol, Sch Perfume & Aroma Technol, Shanghai 200233, Peoples R China
基金
北京市自然科学基金; 中国国家自然科学基金;
关键词
Nanocapsules; Encapsulation; Fragrance; Biocompatibility; Simple operation; CONTROLLED-RELEASE; ESSENTIAL OIL;
D O I
10.1016/j.cclet.2018.09.008
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Fragranced products are wildly used in our daily life. However, their storage, application and quality are severely influenced by their strong volatility. In order to overcome these natural defects of fragrances, fragrance encapsulation approaches have been developed recently. In this study, a mild, simple and low-cost method of fragrance encapsulation was invented. Liposomes composed of soya Iecithin/DSPE-PEG2000/PLGA were prepared to encapsulate lily fragrance (LF). And these nanosized fragrance products was named LF-NPs. The hydrodynamic diameters of LF-NPs were approximately 100 nm and their encapsulation efficiency was up to 21.9%. Besides, LF-NPs could also prolong the release time of lily fragrance. Finally, the cytotoxicity tests indicated that LF-NPs offered biocompatibility. Therefore, LF-NPs were expected to have application prospects. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:739 / 742
页数:4
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