Streptococcus pneumoniae serotypes with meningeal tropism in cases of invasive pneumococcal disease. Community of Madrid, 2007-2018

被引：1
作者：
Carlos Sanz, Juan [1 ,2 ]
de Miguel, Sara [3 ]
Ordobas, Maria [3 ]
Garcia Comas, Luis [3 ]
机构：
[1] Ctr Especialidades Med Vicente Soldevilla, Comunidad Madrid, Direcc Gen Salud Publ, Lab Reg Salud Publ,Unidad Microbiol Clin, Madrid, Spain
[2] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain
[3] Serv Epidemiol, Direcc Gen Salud Publ, Comunidad Madrid, Madrid, Spain
来源：
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2020年 / 38卷 / 08期
关键词：
Streptococcus pneumoniae; Serotypes; Cerebrospinal fluid; MENINGITIS; VACCINE;
D O I：
10.1016/j.eimc.2019.11.002
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Introduction: To describe the distribution of Streptococcus pneumoniae serotypes isolated in cerebrospinal fluid (CSF) between 2007-2018 in the Community of Madrid (CM) and to identify those with higher meningeal tropism. Methods: Strains isolated from invasive pneumococcal disease were sent to the Regional Laboratory of Public Health by Microbiology laboratories of public and private hospitals of the CM. The frequency of serotypes from CSF was compared with that observed in other samples. Results: A total of 6,115 strains were processed and 5% (n=304) were isolated from CSF. Seven serotypes (11A, 19F, 23B, 10A, 24F, 23A and 35F) showed a frequency significantly higher in CSF than in other usually sterile samples. Serotypes 24F, 11A and 23B showed high penicillin-resistance. Conclusion: The frequency and resistance of certain pneumococcal serotypes with high meningeal tropism could compromise the treatment of central nervous system infections. (C) 2019 Elsevier Espafia, S.L.U. and Sociedad Espafiola de Enfermedades Infecciosas y Microbiologia Clinica. All rights reserved.
引用
收藏
页码：371 / 374
页数：4
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