Silicon photonic micro-disk resonators for label-free biosensing

被引：130

作者：

Grist, Samantha M. ^{[1
]}

Schmidt, Shon A. ^{[2
]}

Flueckiger, Jonas ^{[1
]}

Donzella, Valentina ^{[1
]}

Shi, Wei ^{[1
]}

Fard, Sahba Talebi ^{[1
]}

Kirk, James T. ^{[2
]}

Ratner, Daniel M. ^{[2
]}

Cheung, Karen C. ^{[1
]}

Chrostowski, Lukas ^{[1
]}

机构：

[1] Univ British Columbia, Dept Elect & Comp Engn, 2332 Main Mall, Vancouver, BC V6T 1Z4, Canada

[2] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA

来源：

OPTICS EXPRESS | 2013年 / 21卷 / 07期

基金：

美国国家科学基金会;

关键词：

REFRACTIVE-INDEX; PROTEIN-A; WAVE-GUIDE; RESONANCE SHIFTS; RING-RESONATOR; BINDING; STREPTAVIDIN; ROUGHNESS; COMPACT; ANTIGEN;

D O I：

10.1364/OE.21.007994

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Silicon photonic biosensors are highly attractive for multiplexed Lab-on-Chip systems. Here, we characterize the sensing performance of 3 mu m TE-mode and 10 mu m dual TE/TM-mode silicon photonic micro-disk resonators and demonstrate their ability to detect the specific capture of biomolecules. Our experimental results show sensitivities of 26 nm/RIU and 142 nm/RIU, and quality factors of 3.3x10(4) and 1.6x10(4) for the TE and TM modes, respectively. Additionally, we show that the large disks contain both TE and TM modes with differing sensing characteristics. Finally, by serializing multiple disks on a single waveguide bus in a CMOS compatible process, we demonstrate a biosensor capable of multiplexed interrogation of biological samples. (c) 2013 Optical Society of America

引用

页码：7994 / 8006

页数：13

共 50 条

[21] SILICON PHOTONIC RESONATOR FOR LABEL-FREE BIO-SENSING APPLICATION
Udomsom, Suruk
Mankong, Ukrit
Theera-Umpon, Nipon
Ittipratheep, Nattapol
Umezawa, Toshimasa
Matsumoto, Atsushi
Yamamoto, Naokatsu
THIRD INTERNATIONAL CONFERENCE ON PHOTONICS SOLUTIONS (ICPS2017), 2018, 10714
[22] A high efficiency label-free photonic biosensor based on vertically stacked ring resonators
C. E. Campanella
C. M. Campanella
F. De Leonardis
V. M. N. Passaro
The European Physical Journal Special Topics, 2014, 223 : 2009 - 2021
[23] Four-channel label-free photonic crystal biosensor using nanocavity resonators
Olyaee S.
Najafgholinezhad S.
Alipour Banaei H.
Photonic Sensors, 2013, 3 (3) : 231 - 236
[24] Label-free optical biosensing at femtomolar detection limit
Sansone, Lucia
Macchia, Eleonora
Taddei, Chiara
Torsi, Luisa
Giordano, Michele
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 255 : 1097 - 1104
[25] New Microphotonic Resonant Devices for Label-Free Biosensing
Ciminelli, Caterina
Dell'Olio, Francesco
Conteduca, Donato
Innone, Filomena
Tatoli, Teresa
Armenise, Mario N.
2016 18TH INTERNATIONAL CONFERENCE ON TRANSPARENT OPTICAL NETWORKS (ICTON), 2016,
[26] All-optical tuning of a diamond micro-disk resonator on silicon
Hill, Paul
Klitis, Charalambos
Guilhabert, Benoit
Sorel, Marc
Gu, Erdan
Dawson, Martin D.
Strain, Michael J.
PHOTONICS RESEARCH, 2020, 8 (03) : 318 - 324
[27] Label-Free cancer cell biosensor based on photonic crystal ring resonator
Baraty, Fatemeh
Hamedi, Samaneh
RESULTS IN PHYSICS, 2023, 46
[28] SILICA NANOPARTICLES COATING IN SILICON NITRIDE PHOTONIC LABEL-FREE BIOSENSING OF S100 CALCIUM-BINDING PROTEIN A6
Udomsom, Suruk
Baipaywad, Phornsawat
Paengnakorn, Pathinan
Mankong, Ukrit
Theera-Umpon, Nipon
Umezawa, Toshimasa
Matsumoto, Atsushi
Kanno, Atsushi
Yamamoto, Naokatsu
Akahane, Kouichi
Mendez-Astudillo, Manuel
Atthi, Nithi
Yamwong, Wittawat
Klunngien, Nipapan
Meananeatra, Rattanawan
Intuyod, Kitti
Pinlaor, Somchai
Kawanishi, Tetsuya
Imai, Kazuo
COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XVIII, 2023, 12395
[29] Label-free biological sensors based on ring resonators
Delage, Andre
Xu, Dan-Xia
Densmore, Adam
Janz, Siegfried
Waldron, Philip
Lapointe, Jean
Lamontagne, Boris
Mischki, Trevor
Lopinski, Gregory
Schmid, Jens
Cheben, Pavel
ICTON 2008: PROCEEDINGS OF 2008 10TH ANNIVERSARY INTERNATIONAL CONFERENCE ON TRANSPARENT OPTICAL NETWORKS, VOL 4, 2008, : 2 - +
[30] Disk-based one-dimensional photonic crystal slabs for label-free immunosensing
Sancho-Fornes, Gabriel
Avella-Oliver, Miguel
Carrascosa, Javier
Fernandez, Estrella
Brun, Eva M.
Maquieira, Angel
BIOSENSORS & BIOELECTRONICS, 2019, 126 : 315 - 323

← 1 2 3 4 5 →