Intervention toolbox to promote immunosuppressant therapy adherence in adult renal transplant recipients

被引：19

作者：

Chisholm-Burns, Marie A. ^{[1
]}

Spivey, Christina A. ^{[1
]}

Sredzinski, Eric ^{[2
]}

Butler, Sheri L. ^{[2
]}

机构：

[1] Univ Tennessee, Coll Pharm, Memphis, TN 38163 USA

[2] Avella Specialty Pharm, Tucson, AZ USA

来源：

JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION | 2012年 / 52卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Renal transplant; adherence (medication); interventions; IMPROVE MEDICATION-ADHERENCE; RANDOMIZED CONTROLLED-TRIAL; ANTIRETROVIRAL THERAPY; NONCOMPLIANCE; NONADHERENCE; IMPACT; PREVALENCE;

D O I：

10.1331/JAPhA.2012.11083

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Objectives: To provide a brief overview of published immunosuppressant therapy (IST) adherence interventions in adult renal transplant recipients (RTRs) and to describe the utility and aspects of an adherence toolbox for adult RTRs. Setting: National independent specialty pharmacy. Practice description: IST adherence is critical to graft survival after a renal transplant. However, IST nonadherence occurs in a large proportion of adult RTRs. Although effective intervention strategies are needed to improve IST adherence, few intervention studies have been conducted in the adult RTR population. To address this gap in the literature, a randomized controlled trial of a patient-specific behavioral contracts intervention to improve IST adherence among adult RTRs has been implemented. Practice innovation: During the behavioral contracts intervention, researchers have developed a toolbox of practical and replicable items and strategies to address forgetfulness and confusion as barriers to IST adherence. Conclusion: An adherence toolbox that includes simple, practical, accessible mechanisms and strategies to improve IST adherence may benefit adult RTRs.

引用

页码：816 / 822

页数：7

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