Impact of hip fracture, heart failure and weight loss on the risk of institutionalization of community-dwelling patients with dementia

被引:11
作者
Harboun, Marc [2 ]
Dorenlot, Pascale [1 ,3 ]
Cohen, Nadia [4 ]
Steinhagen-Thiessen, Elisabeth [1 ]
Ankri, Joel [3 ,5 ]
机构
[1] Charite, Dept Geriatr, EGZB, D-13347 Berlin, Germany
[2] Hop Paul Brousse, Dept Gerontol 2, Villejuif, France
[3] Hop Paul Brousse, INSERM, Unit 687, Villejuif, France
[4] Hop Notre Dame de Bon Secours, Dept Internal Med & Gerontol, Paris, France
[5] Univ Versailles St Quentin Yvelines, Lab St Vieillissement, Paris, France
关键词
institutionalization; dementia; Alzheimer's disease; medical comorbidity; hip fracture; heart failure; weight loss; prospective study; prevention;
D O I
10.1002/gps.2058
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objectives This study sought to identify the influence of medical symptoms and diseases on the risk of nursing home placement in a prospective cohort of newly diagnosed community-dwelling patients with dementia. Study design and setting This study included 348 patients with dementia, consecutively diagnosed, recruited and followed at a geriatric outpatient center (mean age: 81 years, 65.5% with Alzheimer's disease, mean baseline MMSE score: 20.5, mean follow-up: 20.5 months). Results After adjustment for factors commonly associated with institutionalization in this population, hip fracture in the 3 years preceding diagnosis, acute congestive heart failure during follow-up and weight loss of more than 5% in any year during follow-Lip were independently associated with nursing home placement. Conclusion This study confirms the independent contribution of specific medical symptoms and diseases to earlier institutionalization of patients with dementia. These results stress the importance of better knowledge of the specific characteristics of hip fracture, weight loss and congestive heart failure in the context of dementia, to make more effective prevention possible in this patient population. Copyright (C) 2008 John Wiley & Sons, Ltd.
引用
收藏
页码:1245 / 1252
页数:8
相关论文
共 26 条
  • [1] Dementia is the major cause of functional dependence in the elderly:: 3-year follow-up data from a population-based study
    Agüero-Torres, H
    Fratiglioni, L
    Guo, ZC
    Viitanen, M
    von Strauss, E
    Winblad, B
    [J]. AMERICAN JOURNAL OF PUBLIC HEALTH, 1998, 88 (10) : 1452 - 1456
  • [2] Institutionalization in the elderly:: The role of chronic diseases and dementia.: Cross-sectional and longitudinal data from a population-based study
    Agüero-Torres, H
    von Strauss, E
    Viitanen, M
    Winblad, B
    Fratiglioni, L
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 2001, 54 (08) : 795 - 801
  • [3] Andrieu S, 2001, J Nutr Health Aging, V5, P113
  • [4] Developmental and vascular risk factors for Alzheimer's disease
    Borenstein, AR
    Wu, YG
    Mortimer, JA
    Gerard, DSB
    McCormick, WC
    Bowen, JD
    McCurry, S
    Larson, EB
    [J]. NEUROBIOLOGY OF AGING, 2005, 26 (03) : 325 - 334
  • [5] Treating nondementia illnesses in patients with dementia
    Brauner, DJ
    Muir, JC
    Sachs, GA
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (24): : 3230 - 3235
  • [6] Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins
    Casserly, I
    Topol, E
    [J]. LANCET, 2004, 363 (9415) : 1139 - 1146
  • [7] Serious co-morbidity among unselected cancer patients newly diagnosed in the southeastern part of the Netherlands in 1993-1996
    Coebergh, JWW
    Janssen-Heijnen, MLG
    Post, PN
    Razenberg, PPA
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 1999, 52 (12) : 1131 - 1136
  • [8] A prospective study of the effects of behavioral symptoms on the institutionalization of patients with dementia
    de Vugt, ME
    Stevens, F
    Aalten, P
    Lousberg, R
    Jaspers, N
    Verhey, FRJ
    [J]. INTERNATIONAL PSYCHOGERIATRICS, 2005, 17 (04) : 577 - 589
  • [9] Prevalence and impact of medical comorbidity in Alzheimer's disease
    Doraiswamy, PM
    Leon, J
    Cummings, JL
    Marin, D
    Neumann, PJ
    [J]. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2002, 57 (03): : M173 - M177
  • [10] Major depression of dementia as a risk factor for early institutionalization patients living in the community
    Dorenlot, P
    Harboun, M
    Bige, V
    Henrard, JC
    Ankri, J
    [J]. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2005, 20 (05) : 471 - 478