Association between maternal serum uric acid and preeclampsia

被引：23

作者：

Shakarami, Amir ^{[1
]}

Ghafarzadeh, Masoumeh ^{[2
]}

Yari, Fatemeh ^{[3
]}

Fathi, Leila ^{[4
]}

机构：

[1] Lorestan Univ Med Sci, Sch Med, Dept Cardiol, Khorramabad, Iran

[2] Lorestan Univ Med Sci, Sch Med, Dept Obstet & Gynecol, Khorramabad, Iran

[3] Lorestan Univ Med Sci, Dept Reprod Hlth, Khorramabad, Iran

[4] Lorestan Univ Med Sci, Dept Midwifery, Khorramabad, Iran

来源：

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY | 2022年 / 128卷 / 06期

关键词：

Preeclampsia; serum levels; uric acid; pregnant; PREGNANCY; HYPERTENSION;

D O I：

10.1080/13813455.2020.1773863

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Objective:The aim of this study is to compare the changes in serum uric acid levels among preeclamptic pregnant women and healthy pregnant women. Methods:Two hundred and twenty-four (224) pregnant women were enrolled. Serum uric acid levels were analysed in the two groups at the time of referral and prior to the delivery. Results:The mean uric acid in all pregnant women was 5.61 mg/dL. The mean uric acid in women with preeclampsia was 6.51 +/- 1.53 and in normotensive women was 4.72 +/- 1.58, which was seen significant. The mean age of the mother, gestational age and BMI were not significant with the levels of uric acid. The elevation in serum levels of uric acid increased the risk of preeclampsia by 1.98 folds. Conclusion:There is a significant increase in the serum levels of uric acid in pregnant women with preeclampsia as compared to normotensive women. This can be one of a significant indicator of preeclampsia.

引用

页码：1434 / 1437

页数：4

共 22 条

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