Carboxylic fullerene C60 derivatives: efficient microbicides against herpes simplex virus and cytomegalovirus infections in vitro

被引：35

作者：

Fedorova, Nataliya E. ^{[1
]}

Klimova, Regina R. ^{[1
]}

Tulenev, Yurii A. ^{[1
]}

Chichev, Evgenii V. ^{[1
]}

Kornev, Alexey B. ^{[2
]}

Troshin, Pavel A. ^{[2
]}

Kushch, Alla A. ^{[1
]}

机构：

[1] DI Ivanovskii Inst Virol, Moscow 123098, Russia

[2] Russian Acad Sci, Inst Problems Chem Phys, Chernogolovka 142432, Moscow Region, Russia

来源：

MENDELEEV COMMUNICATIONS | 2012年 / 22卷 / 05期

关键词：

AMPHIPATHIC DNA POLYMERS; ANTIVIRAL ACTIVITY; HIV; GANCICLOVIR; PROTECT; CELLS;

D O I：

10.1016/j.mencom.2012.09.009

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Some carboxylic fullerene C-60 derivatives produced by Friedel-Crafts arylation of C60Cl6, whose potassium salts are water-soluble, exhibit low cytotoxicity and high antiviral activity against herpes simplex virus and human cytomegalovirus.

引用

页码：254 / 256

页数：3

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