Treatment Update of Sensitized Pediatric Kidney Transplant Recipients: A Review

被引：4
作者：
Otukesh, Hasan [1 ]
Hoseini, Rozita [2 ]
Rahimzadeh, Nahid [1 ]
机构：
[1] Univ Tehran Med Sci, Pediat Transplantat Dialysis Res Ctr, Tehran, Iran
[2] Labafi Nejad Hosp, Tehran, Iran
来源：
EXPERIMENTAL AND CLINICAL TRANSPLANTATION | 2012年 / 10卷 / 06期
关键词：
Renal transplant; Highly sensitized recipients; Children; INTRAVENOUS IMMUNE GLOBULIN; RENAL-TRANSPLANT; CROSS-MATCH; LIVING-DONOR; MYCOPHENOLATE-MOFETIL; IMMUNOGLOBULIN; ANTIBODY; DESENSITIZATION; REJECTION; PLASMAPHERESIS;
D O I：
10.6002/ect.2012.0124
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
Sensitization of recipients is an increasing problem in children. Some case series in children exist comparing the diverse desensitizing protocols. These protocols include intravenous immunoglobulin, cytomegalovirus immune globulin, plasmapheresis, and some adjunctive therapies such as rituximab. Desensitizing protocols have advantages and disadvantages. Clinical trials are required to determine suitable protocols for sensitized pediatric recipients. We performed a systematic review of these protocols in children. A massive search was done in PubMed, Embase, and the Cochrane library system. The results of these studies are compared.
引用
收藏
页码：523 / 530
页数：8
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