The role of aldosterone in kidney diseases and hypertension. Is it worth using mineralocorticoid receptor antagonists in clinical practice?

被引：1
|
作者：
Donderski, Rafal [1 ]
Manitius, Jacek [1 ]
机构：
[1] Nicolaus Copernicus Univ, Coll Med Bydgoszcz, Dept Nephrol Hypertens & Internal Med, Torun, Poland
来源：
ARTERIAL HYPERTENSION | 2019年 / 23卷 / 01期
关键词：
aldosterone; chronic kidney disease; hypertension; cardiovascular risk; aldosterone antagonists; STAGE RENAL-DISEASE; RESISTANT HYPERTENSION; ALDACTONE THERAPY; HEART-FAILURE; DOUBLE-BLIND; SPIRONOLACTONE; HEMODIALYSIS; FIBROSIS; PROGRESSION; STIFFNESS;
D O I：
10.5603/AH.a2018.0016
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Aldosterone is a mineralocorticoid hormone which plays a pivotal role in water and electrolytes balance. Moreover, aldosterone exerts a deleterious influence on the cardiovascular system and kidneys. In this review, we wanted to show mechanisms of aldosterone related organ damage, the role of aldosterone in kidney diseases, hypertension and therapeutic benefits related with aldosterone receptors blockade.
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页码：1 / 7
页数：7
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