Synthesis of novel amidoalkyl naphthol-based azo dyes and evaluation of their antimicrobial activities

被引：5

作者：

Bananezhad, Behjat ^{[1
]}

Islami, Mohammad Reza ^{[1
]}

Khabazzadeh, Hojatollah ^{[1
]}

机构：

[1] Shahid Bahonar Univ Kerman, Dept Chem, Kerman 7616914111, Iran

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2019年 / 16卷 / 04期

关键词：

Multi-component reactions (MCRs); Diazonium salt; Azo compound; Amidoalkylnaphthols; Octahydro-1H-xanthen; ONE-POT SYNTHESIS; SCHIFF-BASES; EFFICIENT CATALYST; DERIVATIVES; ANALOGS;

D O I：

10.1007/s13738-018-1563-0

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Several new azo-substituted amidoalkyl naphthol derivatives were synthesized by coupling of octahydro-1H-xanthen and phenol nucleus with diazotized 4-amino benzamide and conversion of the coupling product to amidoalkyl naphthols. This is the first report on the synthesis of amidoalkyl naphthol compounds using benzamide with large azo substituents. Furthermore, antimicrobial activities of all new compounds were studied by in vitro experiment. Some synthesized compounds exhibited potential antimicrobial activities which may guarantee their future application in moderate chemotherapy.

引用

页码：865 / 877

页数：13

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