Modulation of Intestinal Flora by Dietary Polysaccharides: A Novel Approach for the Treatment and Prevention of Metabolic Disorders

被引：21
作者：
Zhang, Li [1 ]
Wang, Xinzhou [2 ]
Zhang, Xin [2 ]
机构：
[1] China Univ Min & Technol, Dept Phys Educ, Beijing 100083, Peoples R China
[2] Ningbo Univ, Dept Food Sci & Engn, Ningbo 315211, Peoples R China
来源：
FOODS | 2022年 / 11卷 / 19期
关键词：
intestinal flora; dietary polysaccharides; metabolic disorders; GUT MICROBIOTA; DIABETES-MELLITUS; INDUCED HYPERLIPIDEMIA; INSULIN SENSITIVITY; INFLAMMATION; MODEL;
D O I：
10.3390/foods11192961
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Intestinal flora is numerous and diverse, and play a key role in maintaining human health. Dietary polysaccharides are widely present in the daily diet and have a moderating effect on the intestinal flora. Past studies have confirmed that intestinal flora is involved in the metabolic process in the human body, and the change in intestinal flora structure is closely related to the metabolic disorders in the human body. Therefore, regulating intestinal flora through dietary polysaccharides is an effective way to treat and prevent common metabolic diseases and has great research value. However, this area has not received enough attention. In this review, we provide an overview of the modulatory effects of dietary polysaccharides on intestinal flora and the key role of intestinal flora in improving metabolic disorders in humans. In addition, we highlight the therapeutic and preventive effects of intestinal flora modulation through dietary polysaccharides on metabolic disorders, aiming to find new ways to treat metabolic disorders and facilitate future exploration in this field.
引用
收藏
页数：15
相关论文
共 50 条
[21]   Modulation of cyclophosphamide-induced immunosuppression and intestinal flora in broiler by deep eutectic solvent extracted polysaccharides of Acanthopanax senticosus [J].
Su, Jianqing ;
Xue, Jiaojiao ;
Wang, Xueyan ;
Zhang, Rui ;
Zhang, Xueping ;
Yang, Yaosen ;
Chu, Xiuling .
FRONTIERS IN VETERINARY SCIENCE, 2024, 11
[22]   The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders [J].
Kong, Hanrui ;
Yang, Jun ;
Wang, Xiaojing ;
Mamat, Nuramina ;
Xie, Guoxuan ;
Zhang, Jing ;
Zhao, Huixin ;
Li, Jinyu .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 265
[23]   Liubao brick tea activates the PI3K-Akt signaling pathway to lower blood glucose, metabolic disorders and insulin resistance via altering the intestinal flora [J].
Zhu, Jiangxiong ;
Wu, Meirong ;
Zhou, Hui ;
Cheng, Lizeng ;
Wei, Xinlin ;
Wang, Yuanfeng .
FOOD RESEARCH INTERNATIONAL, 2021, 148
[24]   The Sanbi Decoction alleviates intervertebral disc degeneration in rats through intestinal flora and serum metabolic homeostasis modulation [J].
Wang, Nan ;
Chen, Shuang ;
Xie, Yimin ;
Liu, Xin ;
Xi, Zhipeng ;
Li, Jingchi ;
Xue, Congyang ;
Deng, Rongrong ;
Min, Wen ;
Kang, Ran ;
Xie, Lin .
PHYTOMEDICINE, 2024, 127
[25]   Gut Microbiota as a Target in the Pathogenesis of Metabolic Disorders: A New Approach to Novel Therapeutic Agents [J].
Ejtahed, H. -S. ;
Soroush, A. -R. ;
Angoorani, P. ;
Larijani, B. ;
Hasani-Ranjbar, S. .
HORMONE AND METABOLIC RESEARCH, 2016, 48 (06) :349-358
[26]   Intestinal flora composition and fecal metabolic phenotype in elderly patients with sleep disorders combined with type 2 diabetes [J].
Yin, Zhuohao ;
Xie, Huaze ;
Liu, Fuyuan ;
Kong, Xue ;
Chen, Wei ;
Gong, Yangfan ;
Ge, Wei .
AGING MEDICINE, 2024, 7 (06) :689-698
[27]   Dietary supplementation with polysaccharides from Rhizoma dioscoreae resulting in the enhanced immunity and the structural modulation of the intestinal microbiota in Luciobarbus capito [J].
Sun, Yuan ;
Hu, Xiaowei ;
Meng, Xianwei ;
Liu, Rui ;
Zhao, Zhigang ;
Wang, Shihui ;
Zhang, Rui ;
Guo, Kun ;
Luo, Liang .
AQUACULTURE, 2023, 577
[28]   Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders [J].
Fiorucci, Stefano ;
Distrutti, Eleonora .
TRENDS IN MOLECULAR MEDICINE, 2015, 21 (11) :702-714
[29]   Proanthocyanidins: Impact on Gut Microbiota and Intestinal Action Mechanisms in the Prevention and Treatment of Metabolic Syndrome [J].
Redondo-Castillejo, Rocio ;
Garcimartin, Alba ;
Hernandez-Martin, Marina ;
Elvira Lopez-Oliva, Maria ;
Bocanegra, Aranzazu ;
Macho-Gonzalez, Adrian ;
Bastida, Sara ;
Benedi, Juana ;
Sanchez-Muniz, Francisco J. .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (06)
[30]   A mixture of four dietary fibres ameliorates adiposity and improves metabolic profile and intestinal health in cafeteria-fed obese rats: an integrative multi-omics approach [J].
Estanyol-Torres, Nuria ;
Domenech-Coca, Cristina ;
Gonzalez-Dominguez, Raul ;
Minarro, Antonio ;
Reverter, Ferran ;
Antonio Moreno-Munoz, Jose ;
Jimenez, Jesus ;
Martin-Palomas, Manel ;
Castellano-Escuder, Pol ;
Mostafa, Hamza ;
Garcia-Vallve, Santi ;
Abasolo, Nerea ;
Rodriguez, Miguel A. ;
Torrell, Helena ;
del Bas, Josep M. ;
Sanchez-Pla, Alex ;
Caimari, Antoni ;
Mas-Capdevila, Anna ;
Andres-Lacueva, Cristina ;
Crescenti, Anna .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2023, 111
12345