Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications

被引：6

作者：

Pollacco, D. A. ^{[1
]}

Conti, M. Caligari ^{[2
]}

Farrugia, L. ^{[1
]}

Wismayer, P. Schembri ^{[3
]}

Farina, L. ^{[4
,5
,6
]}

Sammut, C., V ^{[1
]}

机构：

[1] Univ Malta, Fac Sci, Dept Phys, Msida 2080, Msd, Malta

[2] Univ Malta, Fac Engn, Dept Met & Mat Engn, Msida 2080, Msd, Malta

[3] Univ Malta, Fac Med & Surg, Dept Anat, Msida 2080, Msd, Malta

[4] Sapienza Univ, Dept Informat Engn Elect & Telecommun, Rome, Italy

[5] Natl Univ Ireland Galway, Translat Med Device Lab, Galway, Ireland

[6] Natl Univ Ireland Galway, CURAM, Galway, Ireland

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2019年 / 64卷 / 09期

关键词：

tissue mimicking solutions; muscle; adipose; microwave imaging; microwave ablation; BREAST-CANCER DETECTION; PHANTOM; POLYACRYLAMIDE; BAND;

D O I：

10.1088/1361-6560/ab0dda

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buffered saline (PBS) and Ringer's solutions were synthesized to mimic in vivo and ex vivo muscle tissues. Solutions consisting of concentrations of peanut oil and Triton X-100 (TX) in PBS and Ringer's solutions were also synthesized to mimic in vivo and ex vivo adipose tissue. Results were then analysed and compared to measured dielectric properties of in vivo and ex vivo biological tissues from another previous study. Good agreement with said dielectric property measurements were obtained since the solutions from this study yielded low RMSE and RMSRE values. This implied that such solutions can be utilized in the construction of human body phantoms for narrowband and ultra-wideband microwave devices for near field breast cancer imaging.

引用

页数：16

共 33 条

[1] USE OF POLYACRYLAMIDE AS A TISSUE-EQUIVALENT MATERIAL IN THE MICROWAVE RANGE [J].

ANDREUCCETTI, D ;

BINI, M ;

IGNESTI, A ;

OLMI, R ;

RUBINO, N ;

VANNI, R .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1988, 35 (04) :275-277

[2]

[Anonymous], 2013, IEEE Std 1528-2013 (Revision of IEEE Std 1528-2003), P1, DOI DOI 10.1109/IEEESTD.2013.6589093

[3]

[Anonymous], 1999, MEAS GOOD PRACT GUID

[4]

Belk K., 2015, DUES MUSCLE TISSUE C

[5]

Chang Chia-Yu, 2009, Acta Neurol Taiwan, V18, P231

[6] A conductive plastic for simulating biological tissue at microwave frequencies [J].

Chang, JT ;

Fanning, MW ;

Meaney, PM ;

Paulsen, KD .

IEEE TRANSACTIONS ON ELECTROMAGNETIC COMPATIBILITY, 2000, 42 (01) :76-81

[7]

CHOU CK, 1984, BIOELECTROMAGNETICS, V5, P435, DOI 10.1002/bem.2250050408

[8] Confocal microwave Imaging for breast cancer detection: Localization of tumors in three dimensions [J].

Fear, EC ;

Li, X ;

Hagness, SC ;

Stuchly, MA .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2002, 49 (08) :812-822

[9]

Grace-Martin K, 2019, ASSESSING FIT REGRES

[10]

Ito K, 2007, NUMERICAL EXPT HUMAN, P6

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