Exome sequencing highlights the role of wild-relative introgression in shaping the adaptive landscape of the wheat genome

被引：224

作者：

He, Fei ^{[1
]}

Pasam, Raj ^{[2
]}

Shi, Fan ^{[2
]}

Kant, Surya ^{[2
]}

Keeble-Gagnere, Gabriel ^{[2
]}

Kay, Pippa ^{[2
]}

Forrest, Kerrie ^{[2
]}

Fritz, Allan ^{[3
]}

Hucl, Pierre ^{[4
]}

Wiebe, Krystalee ^{[4
]}

Knox, Ron ^{[5
]}

Cuthbert, Richard ^{[5
]}

Pozniak, Curtis ^{[4
]}

Akhunova, Alina ^{[1
,6
]}

Morrell, Peter L. ^{[7
]}

Davies, John P. ^{[8
]}

Webb, Steve R. ^{[8
]}

Spangenberg, German ^{[2
,9
]}

Hayes, Ben ^{[2
,10
]}

Daetwyler, Hans ^{[2
,9
]}

Tibbits, Josquin ^{[2
,9
]}

Hayden, Matthew ^{[2
,9
]}

Akhunov, Eduard ^{[1
]}

机构：

[1] Kansas State Univ, Dept Plant Pathol, Throckmorton Hall, Manhattan, KS 66506 USA

[2] Ctr AgriBiosci, AgriBio, Agr Victoria, Bundoora, Vic, Australia

[3] Kansas State Univ, Dept Agron, Manhattan, KS 66506 USA

[4] Univ Saskatchewan, Ctr Crop Dev, Saskatoon, SK, Canada

[5] Swift Current Res & Dev Ctr, Swift Current, SK, Canada

[6] Kansas State Univ, Integrated Genom Facil, Manhattan, KS 66506 USA

[7] Univ Minnesota, Dept Agron & Plant Genet, St Paul, MN USA

[8] DowDuPont, Div Agr, Corteva Agrisci, Indianapolis, IN USA

[9] La Trobe Univ, Sch Appl Syst Biol, Bundoora, Vic, Australia

[10] Univ Queensland, Ctr Anim Sci, Queensland Alliance Agr & Food Innovat, St Lucia, Qld, Australia

来源：

NATURE GENETICS | 2019年 / 51卷 / 05期

基金：

美国食品与农业研究所; 美国国家科学基金会;

关键词：

GENE FLOW; MOLECULAR CHARACTERIZATION; DELETERIOUS MUTATIONS; DOMESTICATION; DIVERSITY; PROGENITOR; SELECTION; POPULATIONS; IMPROVEMENT; EVOLUTION;

D O I：

10.1038/s41588-019-0382-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Introgression is a potential source of beneficial genetic diversity. The contribution of introgression to adaptive evolution and improvement of wheat as it was disseminated worldwide remains unknown. We used targeted re-sequencing of 890 diverse accessions of hexaploid and tetraploid wheat to identify wild-relative introgression. Introgression, and selection for improvement and environmental adaptation, each reduced deleterious allele burden. Introgression increased diversity genome wide and in regions harboring major agronomic genes, and contributed alleles explaining a substantial proportion of phenotypic variation. These results suggest that historic gene flow from wild relatives made a substantial contribution to the adaptive diversity of modern bread wheat.

引用

页码：896 / +

页数：14

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