A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector

被引：61
作者：
Dong, Ruijiao [1 ]
Su, Yue [1 ]
Yu, Songrui [1 ]
Zhou, Yongfeng [1 ]
Lu, Yunfeng [2 ]
Zhu, Xinyuan [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China
[2] Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 84期
关键词：
DELIVERY; CANCER;
D O I：
10.1039/c3cc46123h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel class of redox-responsive cationic supramolecular polymer with effective DNA condensation ability and H2O2-induced DNA release behavior has been successfully constructed from small molecules. This supramolecular polymer can be used in vitro as a promising nonviral vector for gene therapy.
引用
收藏
页码：9845 / 9847
页数：3
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