A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector

被引：63

作者：

Dong, Ruijiao ^{[1
]}

Su, Yue ^{[1
]}

Yu, Songrui ^{[1
]}

Zhou, Yongfeng ^{[1
]}

Lu, Yunfeng ^{[2
]}

Zhu, Xinyuan ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China

[2] Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 84期

关键词：

DELIVERY; CANCER;

D O I：

10.1039/c3cc46123h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel class of redox-responsive cationic supramolecular polymer with effective DNA condensation ability and H2O2-induced DNA release behavior has been successfully constructed from small molecules. This supramolecular polymer can be used in vitro as a promising nonviral vector for gene therapy.

引用

页码：9845 / 9847

页数：3

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