Behavioral fever in ectothermic vertebrates

被引:73
作者
Rakus, Krzysztof [1 ]
Ronsmans, Maygane [2 ]
Vanderplasschen, Alain [2 ]
机构
[1] Jagiellonian Univ, Dept Evolutionary Immunol, Inst Zool, Gronostajowa 9, PL-30387 Krakow, Poland
[2] Univ Liege, FARAH, Immunol Vaccinol, Fac Vet Med, Liege, Belgium
关键词
Fever; Behavioral fever; Ectotherms; Innate immunity; Pyrogens; Prostaglandins; LIPOPOLYSACCHARIDE-INDUCED FEVER; BLOOD MONONUCLEAR-CELLS; BRAIN ENDOTHELIAL-CELLS; NECROSIS-FACTOR TNF; BODY-TEMPERATURE; PRODUCE FEVER; PYROGENS FAIL; BACTERIAL LIPOPOLYSACCHARIDE; SYSTEMIC INFLAMMATION; ENDOGENOUS PYROGEN;
D O I
10.1016/j.dci.2016.06.027
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
Fever is an evolutionary conserved defense mechanism which is present in both endothermic and ectothermic vertebrates. Ectotherms in response to infection can increase their body temperature by moving to warmer places. This process is known as behavioral fever. In this review, we summarize the current knowledge on the mechanisms of induction of fever in mammals. We further discuss the evolutionary conserved mechanisms existing between fever of mammals and behavioral fever of ectothermic vertebrates. Finally, the experimental evidences supporting an adaptive value of behavioral fever expressed by ectothermic vertebrates are summarized. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:84 / 91
页数:8
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