An unusual case of vancomycin-related systemic reaction accompanied with severe thrombocytopenia mimicking pacemaker-related infective endocarditis: a case report and review of literature

被引：4

作者：

Candemir, Basar ^{[1
,2
]}

Acibuca, Aynur ^{[1
]}

Koca, Cigdem ^{[1
]}

Ozcan, Ozgur Ulas ^{[1
]}

Gerede, Menekse ^{[1
]}

Kaya, Cansin T. ^{[1
]}

机构：

[1] Ankara Univ, Dept Cardiol, TR-06590 Ankara, Turkey

[2] Ankara Univ, Sch Med, Dept Cardiol, Ctr Heart, TR-06590 Ankara, Turkey

来源：

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY | 2013年 / 38卷 / 02期

关键词：

Implantable cardioverter defibrillator; Infective endocarditis; Hematoma; Vancomycin; Thrombocytopenia; DRUG-INDUCED THROMBOCYTOPENIA;

D O I：

10.1007/s10840-012-9738-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive resistant bacteria. In recent years, several cases of vancomycin-associated immune thrombocytopenia have been presented as case reports, but the real incidence of this side effect is still unknown. In this report, we would like to present a case during which we confronted with a great dilemma: urgent removal of whole defibrillator system due to highly suspected infective endocarditis or leaving the defibrillator in place and simply switching vancomycin to another antibiotic agent and wait.

引用

页码：143 / 145

页数：3

共 11 条

[1] Current concepts - Drug-induced immune thrombocytopenia [J].

Aster, Richard H. ;

Bougie, Daniel W. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (06) :580-587

[2] Drug-induced thrombocytopenia: A systematic review of published case reports [J].

George, JN ;

Raskob, GE ;

Shah, SR ;

Rizvi, MA ;

Hamilton, SA ;

Osborne, S ;

Vondracek, T .

ANNALS OF INTERNAL MEDICINE, 1998, 129 (11) :886-890

[3]

Govindarajan R, 1999, AM J HEMATOL, V62, P122, DOI 10.1002/(SICI)1096-8652(199910)62:2<122::AID-AJH14>3.0.CO

[4]

2-R

[5] Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009) [J].

Habib, Gilbert ;

Hoen, Bruno ;

Tornos, Pilar ;

Thuny, Franck ;

Prendergast, Bernard ;

Vilacosta, Isidre ;

Moreillon, Philippe ;

Antunes, Manuel de Jesus ;

Thilen, Ulf ;

Lekakis, John ;

Lengyel, Maria ;

Mueller, Ludwig ;

Naber, Christoph K. ;

Nihoyannopoulos, Petros ;

Moritz, Anton ;

Luis Zamorano, Jose .

EUROPEAN HEART JOURNAL, 2009, 30 (19) :2369-2413

[6]

Kuruppu JC, 1999, AM J HEMATOL, V60, P249, DOI 10.1002/(SICI)1096-8652(199903)60:3<249::AID-AJH20>3.3.CO

[7]

2-8

[8] Drug-induced thrombocytopenia - An updated systematic review, 2006 [J].

Li, Xiaoning ;

Swisher, Karen K. ;

Vesely, Sara K. ;

George, James N. .

DRUG SAFETY, 2007, 30 (02) :185-186

[9] Thrombocytopenia induced by vancomycin-dependent platelet antibody [J].

Mizon, P ;

Kiefel, V ;

Mannessier, L ;

MuellerEckhardt, C ;

Goudemand, J .

VOX SANGUINIS, 1997, 73 (01) :49-51

[10] Vancomycin-induced immune thrombocytopenia [J].

Von Drygalski, Annette ;

Curtis, Brian R. ;

Bougie, Daniel W. ;

McFarland, Janice G. ;

Ahl, Scott ;

Limbu, Indra ;

Baker, Kelty R. ;

Aster, Richard H. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (09) :904-910

← 1 2 →