Cognitive and emotional control of pain and its disruption in chronic pain

被引：1433

作者：

Bushnell, M. Catherine ^{[1
]}

Ceko, Marta ^{[1
]}

Low, Lucie A. ^{[1
]}

机构：

[1] NIH, Natl Ctr Complementary & Alternat Med, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS NEUROSCIENCE | 2013年 / 14卷 / 07期

关键词：

IRRITABLE-BOWEL-SYNDROME; CHRONIC LOW-BACK; ANTERIOR CINGULATE CORTEX; MU-OPIOID RECEPTOR; NOXIOUS THERMAL-STIMULATION; POSTERIOR PARIETAL CORTEX; LONG-TERM POTENTIATION; GRAY-MATTER; DECISION-MAKING; PLACEBO ANALGESIA;

D O I：

10.1038/nrn3516

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Chronic pain is one of the most prevalent health problems in our modern world, with millions of people debilitated by conditions such as back pain, headache and arthritis. To address this growing problem, many people are turning to mind-body therapies, including meditation, yoga and cognitive behavioural therapy. This article will review the neural mechanisms underlying the modulation of pain by cognitive and emotional states -important components of mind-body therapies. It will also examine the accumulating evidence that chronic pain itself alters brain circuitry, including that involved in endogenous pain control, suggesting that controlling pain becomes increasingly difficult as pain becomes chronic.

引用

页码：502 / 511

页数：10

共 184 条

[1] Environmental enrichment reduces mechanical hypersensitivity in neuropathic mice, but fails to abolish the phenotype of CCK2 receptor deficient mice [J].

Abramov, Urho ;

Kurrikoff, Kaido ;

Matsui, Toshimitsu ;

Vasar, Eero .

NEUROSCIENCE LETTERS, 2009, 467 (03) :230-233

[2] Neuropharmacological dissection of placebo analgesia: Expectation-activated opioid systems versus conditioning-activated specific subsystems [J].

Amanzio, M ;

Benedetti, F .

JOURNAL OF NEUROSCIENCE, 1999, 19 (01) :484-494

[3] Expression of IL-1β in supraspinal brain regions in rats with neuropathic pain [J].

Apkarian, A. Vania ;

Lavarello, Simona ;

Randolf, Anke ;

Berra, Hector H. ;

Chialvo, Dante R. ;

Besedovsky, Hugo O. ;

del Rey, Adriana .

NEUROSCIENCE LETTERS, 2006, 407 (02) :176-181

[4] Chronic pain patients are impaired on an emotional decision-making task [J].

Apkarian, AV ;

Sosa, Y ;

Krauss, BR ;

Thomas, PS ;

Fredrickson, BE ;

Levy, RE ;

Harden, RN ;

Chialvo, DR .

PAIN, 2004, 108 (1-2) :129-136

[5] Human brain mechanisms of pain perception and regulation in health and disease [J].

Apkarian, AV ;

Bushnell, MC ;

Treede, RD ;

Zubieta, JK .

EUROPEAN JOURNAL OF PAIN, 2005, 9 (04) :463-484

[6] Chronic back pain is associated with decreased prefrontal and thalamic gray matter density [J].

Apkarian, AV ;

Sosa, Y ;

Sonty, S ;

Levy, RM ;

Harden, RN ;

Parrish, TB ;

Gitelman, DR .

JOURNAL OF NEUROSCIENCE, 2004, 24 (46) :10410-10415

[7]

Apkarian AV, 1998, PAIN MECHANISMS AND MANAGEMENT, P212

[8] Affective pain modulation in fibromyalgia, somatoform pain disorder, back pain, and healthy controls [J].

Arnold, Bettina S. ;

Alpers, Georg W. ;

Suess, Holger ;

Friedel, Eckart ;

Kosmuetzky, Gregor ;

Geier, Antje ;

Pauli, Paul .

EUROPEAN JOURNAL OF PAIN, 2008, 12 (03) :329-338

[9] Oxytocin levels in the posterior pituitary and in the heart are modified by voluntary wheel running [J].

Bakos, J. ;

Hlavacova, N. ;

Makatsori, A. ;

Tybitanclova, K. ;

Zorad, S. ;

Hinghofer-Szalkay, H. ;

Johansson, B. B. ;

Jezova, D. .

REGULATORY PEPTIDES, 2007, 139 (1-3) :96-101

[10] Parsing Pain Perception Between Nociceptive Representation and Magnitude Estimation [J].

Baliki, M. N. ;

Geha, P. Y. ;

Apkarian, A. V. .

JOURNAL OF NEUROPHYSIOLOGY, 2009, 101 (02) :875-887

← 1 2 3 4 5 6 7 8 9 10 →