Stem cells: An eventual treatment option for heart diseases

被引：8
作者：
Bilgimol, Joseph [1 ,2 ]
Ragupathi, Subbareddy [3 ]
Vengadassalapathy, Lakshmanan [2 ]
Senthil, Nathan [4 ]
Selvakumar, Kalimuthu [2 ]
Ganesan, M. [1 ,2 ]
Manjunath, Sadananda [1 ,2 ]
机构：
[1] Micro Therapeut Res Labs Private Ltd, Chennai 600059, Tamil Nadu, India
[2] KMS Hlth Ctr Private Ltd, 50,51 Balaji Nagar,3rd St, Chennai 600050, Tamil Nadu, India
[3] Chettinad Hosp, Chennai 603103, Tamil Nadu, India
[4] Thermo Fisher Sci India Private Ltd, Chennai 600034, Tamil Nadu, India
来源：
WORLD JOURNAL OF STEM CELLS | 2015年 / 7卷 / 08期
关键词：
Bone marrow stem cells; Mesenchymal stem cells; Induced pluripotent stem cells; Heart diseases; Progenitor cells; Stem cells; ENDOTHELIAL PROGENITOR CELLS; ACUTE MYOCARDIAL-INFARCTION; MARROW MONONUCLEAR-CELLS; BONE-MARROW; CARDIOVASCULAR-DISEASE; INTRAMYOCARDIAL INJECTION; CARDIAC REPAIR; GENE-THERAPY; REGENERATION; FAILURE;
D O I：
10.4252/wjsc.v7.i8.1118
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Stem cells are of global excitement for various diseases including heart diseases. It is worth to understand the mechanism or role of stem cells in the treatment of heart failure. Bone marrow derived stem cells are commonly practiced with an aim to improve the function of the heart. The majority of studies have been conducted with acute myocardial infarction and a few has been investigated with the use of stem cells for treating chronic or dilated cardiomyopathy. Heterogeneity in the treated group using stem cells has greatly emerged. Ever increasing demand for any alternative made is of at most priority for cardiomyopathy. Stem cells are of top priority with the current impact that has generated among physicians. However, meticulous selection of proper source is required since redundancy is clearly evident with the present survey. This review focuses on the methods adopted using stem cells for heart diseases and outcomes that are generated so far with an idea to determine the best therapeutic possibility in order to fulfill the present demand.
引用
收藏
页码：1118 / 1126
页数：9
相关论文
共 92 条
[81]   The potential and challenges of using stem cells for cardiovascular repair and regeneration [J].
Sun, Qisi ;
Zhang, Zhonge ;
Sun, Zhongjie .
GENES & DISEASES, 2014, 1 (01) :113-119
[82]   Cell-based cardiovascular repair and regeneration in acute myocardial infarction and chronic ischemic cardiomyopathy - current status and future developments [J].
Templin, Christian ;
Luescher, Thomas F. ;
Landmesser, Ulf .
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2011, 55 (4-5) :407-417
[83]   Cardiac stem and progenitor cell biology for regenerative medicine [J].
Torella, D ;
Ellison, GA ;
Nadal-Ginard, B ;
Indolfi, C .
TRENDS IN CARDIOVASCULAR MEDICINE, 2005, 15 (06) :229-236
[84]   Clinical trials for stem cell therapies [J].
Trounson, Alan ;
Thakar, Rahul G. ;
Lomax, Geoff ;
Gibbons, Don .
BMC MEDICINE, 2011, 9
[85]  
Van Oorschot AAM, 2010, PANMINERVA MED, V52, P97
[86]  
Vrtovec Bojan, 2013, Methodist Debakey Cardiovasc J, V9, P6
[87]   Circulating endothelial progenitor cells, C-reactive protein and severity of coronary stenosis in Chinese patients with coronary artery disease [J].
Wang, Hai-Ya ;
Gao, Ping-Jin ;
Ji, Kai-Da ;
Shen, Wei-Feng ;
Fan, Chun-Ling ;
Lu, Lin ;
Zhu, Ding-Liang .
HYPERTENSION RESEARCH, 2007, 30 (02) :133-141
[88]   Manufacturing considerations for clinical uses of therapies derived from stem cells [J].
Weber, Darin J. .
STEM CELL TOOLS AND OTHER EXPERIMENTAL PROTOCOLS, 2006, 420 :410-430
[89]   A New Direction for Cardiac Regeneration Therapy Application of Synergistically Acting Epicardium-Derived Cells and Cardiomyocyte Progenitor Cells [J].
Winter, Elizabeth M. ;
van Oorschot, Angelique A. M. ;
Hogers, Bianca ;
van der Graaf, Linda M. ;
Doevendans, Pieter A. ;
Poelmann, Robert E. ;
Atsma, Douwe E. ;
Gittenberger-de Groot, Adriana C. ;
Goumans, Marie Jose .
CIRCULATION-HEART FAILURE, 2009, 2 (06) :643-653
[90]   Combined Therapy With Simvastatin and Bone Marrow-Derived Mesenchymal Stem Cells Increases Benefits in Infarcted Swine Hearts [J].
Yang, Yue-Jin ;
Qian, Hai-Yan ;
Huang, Ji ;
Li, Jian-Jun ;
Gao, Run-Lin ;
Dou, Ke-Fei ;
Yang, Guo-Sheng ;
Willerson, James T. ;
Geng, Yong-Jian .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2009, 29 (12) :2076-U209
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