Stem cells: An eventual treatment option for heart diseases

被引:8
作者
Bilgimol, Joseph [1 ,2 ]
Ragupathi, Subbareddy [3 ]
Vengadassalapathy, Lakshmanan [2 ]
Senthil, Nathan [4 ]
Selvakumar, Kalimuthu [2 ]
Ganesan, M. [1 ,2 ]
Manjunath, Sadananda [1 ,2 ]
机构
[1] Micro Therapeut Res Labs Private Ltd, Chennai 600059, Tamil Nadu, India
[2] KMS Hlth Ctr Private Ltd, 50,51 Balaji Nagar,3rd St, Chennai 600050, Tamil Nadu, India
[3] Chettinad Hosp, Chennai 603103, Tamil Nadu, India
[4] Thermo Fisher Sci India Private Ltd, Chennai 600034, Tamil Nadu, India
来源
WORLD JOURNAL OF STEM CELLS | 2015年 / 7卷 / 08期
关键词
Bone marrow stem cells; Mesenchymal stem cells; Induced pluripotent stem cells; Heart diseases; Progenitor cells; Stem cells; ENDOTHELIAL PROGENITOR CELLS; ACUTE MYOCARDIAL-INFARCTION; MARROW MONONUCLEAR-CELLS; BONE-MARROW; CARDIOVASCULAR-DISEASE; INTRAMYOCARDIAL INJECTION; CARDIAC REPAIR; GENE-THERAPY; REGENERATION; FAILURE;
D O I
10.4252/wjsc.v7.i8.1118
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Stem cells are of global excitement for various diseases including heart diseases. It is worth to understand the mechanism or role of stem cells in the treatment of heart failure. Bone marrow derived stem cells are commonly practiced with an aim to improve the function of the heart. The majority of studies have been conducted with acute myocardial infarction and a few has been investigated with the use of stem cells for treating chronic or dilated cardiomyopathy. Heterogeneity in the treated group using stem cells has greatly emerged. Ever increasing demand for any alternative made is of at most priority for cardiomyopathy. Stem cells are of top priority with the current impact that has generated among physicians. However, meticulous selection of proper source is required since redundancy is clearly evident with the present survey. This review focuses on the methods adopted using stem cells for heart diseases and outcomes that are generated so far with an idea to determine the best therapeutic possibility in order to fulfill the present demand.
引用
收藏
页码:1118 / 1126
页数:9
相关论文
共 92 条
  • [1] THERAPEUTICS Doubts over heart stem-cell therapy
    Abbott, Alison
    [J]. NATURE, 2014, 509 (7498) : 15 - 16
  • [2] Stem Cell Therapy in Heart Diseases: A Review of Selected New Perspectives, Practical Considerations and Clinical Applications
    Abdelwahid, Eltyeb
    Siminiak, Tomasz
    Cesar Guarita-Souza, Luiz
    Athayde Teixeira de Carvalho, Katherine
    Gallo, Pasquale
    Shim, Winston
    Condorelli, Gianluigi
    [J]. CURRENT CARDIOLOGY REVIEWS, 2011, 7 (03) : 201 - 212
  • [3] Aronow Wilbert S., 2007, Comprehensive Therapy, V33, P223, DOI 10.1007/s12019-007-8019-2
  • [4] Usefulness of intramyocardial injection of autologous bone marrow-derived mononuclear cells in patients with severe angina pectoris and stress-induced myocardial ischemia
    Beeres, Saskia L. M. A.
    Bax, Jeroen J.
    Kaandorp, Theodorus A. M.
    Zeppenfeld, Katja
    Lamb, Hildo J.
    Dibbets-Schneider, Petra
    Stokkel, Marcel P. M.
    Fibbe, Willem E.
    de Roos, Albert
    van der Wall, Ernst E.
    Schalij, Martin J.
    Atsma, Douwe E.
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2006, 97 (09) : 1326 - 1331
  • [5] Beeres SLMA, 2006, J NUCL MED, V47, P574
  • [6] Stem cell therapy for cardiac disease
    Bernstein, Harold S.
    Srivastava, Deepak
    [J]. PEDIATRIC RESEARCH, 2012, 71 (04) : 491 - 499
  • [7] Potential risks of bone marrow cell transplantation into infarcted hearts
    Breitbach, Martin
    Bostani, Toktam
    Roell, Wilhelm
    Xia, Ying
    Dewald, Oliver
    Nygren, Jens M.
    Fries, Jochen W. U.
    Tiemann, Klaus
    Bohlen, Heribert
    Hescheler, Juergen
    Welz, Armin
    Bloch, Wilhelm
    Jacobsen, Sten Eirik W.
    Fleischmann, Bernd K.
    [J]. BLOOD, 2007, 110 (04) : 1362 - 1369
  • [8] Correlations between progression of coronary artery disease and circulating endothelial progenitor cells
    Briguori, Carlo
    Testa, Ugo
    Riccioni, Roberta
    Colombo, Antonio
    Petrucci, Eleonora
    Condorelli, Gerolama
    Mariani, Gualtiero
    D'Andrea, Davide
    De Micco, Francesca
    Rivera, Natalia V.
    Puca, Annibale Alessandro
    Peschle, Cesare
    Condorelli, Gianluigi
    [J]. FASEB JOURNAL, 2010, 24 (06) : 1981 - 1988
  • [9] Hematopoietic stem cell transplantation for cardiac and peripheral vascular disease
    Burt, R
    Pearce, W
    Luo, K
    Oyama, Y
    Davidson, C
    Beohar, N
    Gheorghiade, M
    [J]. BONE MARROW TRANSPLANTATION, 2003, 32 (Suppl 1) : S29 - S31
  • [10] Cardiovascular Disease in the Developing World
    Celermajer, David S.
    Chow, Clara K.
    Marijon, Eloi
    Anstey, Nicholas M.
    Woo, Kam S.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 60 (14) : 1207 - 1216