Assessment and treatment of neurogenic dysphagia in stroke and Parkinson's disease

被引:24
作者
Cosentino, Giuseppe [1 ,2 ]
Todisco, Massimiliano [1 ,2 ]
Giudice, Carla [2 ,3 ]
Tassorelli, Cristina [2 ,3 ,4 ]
Alfonsi, Enrico [1 ]
机构
[1] IRCCS Mondino Fdn, Translat Neurophysiol Res Unit, Pavia, Italy
[2] Univ Pavia, Dept Brain & Behav Sci, Pavia, Italy
[3] IRCCS Mondino Fdn, Headache Sci & Neurorehabil Ctr, Pavia, Italy
[4] IRCCS Mondino Fdn, Headache Sci & Neurorehabil Ctr, Via Mondino 2, I-27100 Pavia, Italy
关键词
neurogenic dysphagia; oropharyngeal dysphagia; Parkinson's disease; stroke; swallowing impairment; NEUROMUSCULAR ELECTRICAL-STIMULATION; BOTULINUM TOXIN INJECTION; OROPHARYNGEAL DYSPHAGIA; POSTSTROKE DYSPHAGIA; MANOMETRIC ABNORMALITIES; DYSFUNCTION; OUTCOMES; THERAPY; INTERVENTIONS; QUESTIONNAIRE;
D O I
10.1097/WCO.0000000000001117
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose of reviewNeurogenic dysphagia worsens quality of life and prognosis of patients with different neurological disorders. Management of neurogenic dysphagia can be challenging. This review provides a comprehensive overview of current evidence on screening, diagnosis, and treatment of neurogenic dysphagia in stroke and Parkinson's disease, suggesting clues for clinical practice.Recent findingsThe pros and cons of diagnostic techniques are discussed in the light of updated evidence. Findings from recent meta-analyses of different treatment approaches, including traditional dysphagia therapy, peripheral and central neurostimulation techniques, and treatment with botulinum toxin, are critically discussed, emphasizing inconsistencies and controversial issues.Screening tests and clinical swallow examination should be routinely performed in neurological patients at risk for dysphagia. In patients testing positive for dysphagia, first-line instrumental investigations, represented by fiberoptic endoscopic evaluation of swallowing or videofluoroscopic swallow study, should be performed to confirm the presence of dysphagia, to assess its severity, and to inform the treatment. Second-line and third-line instrumental methods can be used in selected patients to clarify specific pathophysiological aspects of oropharyngeal dysphagia. Treatment strategies should be personalized, and combination of traditional dysphagia therapy with innovative treatment approaches may increase the chance of restoring effective and safe swallowing.
引用
收藏
页码:741 / 752
页数:12
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