Obatoclax effects on MCL1 addiction in mesothelioma and activity in vivo

被引：1
|
作者：
McTavish, N.
McCoy, F.
Paul, I.
Busacca, S.
Fennell, D. A.
机构：
[1] Queens Univ Belfast, Belfast, Antrim, North Ireland
[2] Ctr Canc Res & Cell Biol, Belfast, Antrim, North Ireland
[3] Queens Univ Belfast, Ctr Canc Res & Cell Biol, Belfast, Antrim, North Ireland
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2011年 / 29卷 / 15期
关键词：
D O I：
10.1200/jco.2011.29.15_suppl.e13539
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
e13539
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Bortezomib resistance in mesothelioma is associated with NOXA downregulation: reversal by the MCL-1 antagonist obatoclax
    Chacko, Alex D.
    Busacca, Sara
    Barbone, Dario
    Crawford, Nyree
    Al Rashid, Shahnaz
    Bertino, Pietro
    Mutti, Luciano
    Gaudino, Giovanni
    Broaddus, V. C.
    Fennell, Dean A.
    JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (09) : S363 - S363
  • [2] Resistance to HSP90 inhibition involving loss of MCL1 addiction
    Busacca, S.
    Law, E. W. P.
    Powley, I. R.
    Proia, D. A.
    Sequeira, M.
    Le Quesne, J.
    Klabatsa, A.
    Edwards, J. M.
    Matchett, K. B.
    Luo, J. L.
    Pringle, J. H.
    El-Tanani, M.
    MacFarlane, M.
    Fennell, D. A.
    ONCOGENE, 2016, 35 (12) : 1483 - 1492
  • [3] Resistance to HSP90 inhibition involving loss of MCL1 addiction
    S Busacca
    E W P Law
    I R Powley
    D A Proia
    M Sequeira
    J Le Quesne
    A Klabatsa
    J M Edwards
    K B Matchett
    J L Luo
    J H Pringle
    M El-Tanani
    M MacFarlane
    D A Fennell
    Oncogene, 2016, 35 : 1483 - 1492
  • [4] Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression
    Champa, Devora
    Russo, Marika A.
    Liao, Xiao-Hui
    Refetoff, Samuel
    Ghossein, Ronald A.
    Di Cristofano, Antonio
    ENDOCRINE-RELATED CANCER, 2014, 21 (05) : 755 - 767
  • [5] MCL1 interacts with PCNA and modulates cell cycle progression in vivo
    Fujise, K
    Yeh, ETH
    CIRCULATION, 1999, 100 (18) : 616 - 617
  • [6] Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma
    Laetsch, T. W.
    Liu, X.
    Vu, A.
    Sliozberg, M.
    Vido, M.
    Elci, O. U.
    Goldsmith, K. C.
    Hogarty, M. D.
    CELL DEATH & DISEASE, 2014, 5 : e1072 - e1072
  • [7] Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma
    T W Laetsch
    X Liu
    A Vu
    M Sliozberg
    M Vido
    O U Elci
    K C Goldsmith
    M D Hogarty
    Cell Death & Disease, 2014, 5 : e1072 - e1072
  • [8] Lipid-Dependent Bimodal MCL1 Membrane Activity
    Landeta, Olatz
    Garcia Valero, Juan
    Flores-Romero, Hector
    Bustillo-Zahalbeitia, Itsasne
    Landajuela, Ane
    Garcia-Porras, Miguel
    Terrones, Oihana
    Basanez, Gorka
    ACS CHEMICAL BIOLOGY, 2014, 9 (12) : 2852 - 2863
  • [9] MCL1 as putative target in pancreatoblastoma
    Reissig, Timm M.
    Uhrig, Sebastian
    Jost, Philipp J.
    Luchini, Claudio
    Vicentini, Caterina
    Liffers, Sven-Thorsten
    Allgaeuer, Michael
    Adsay, Volkan
    Scarpa, Aldo
    Lawlor, Rita Teresa
    Froehling, Stefan
    Stenzinger, Albrecht
    Kloeppel, Gunter
    Schildhaus, Hans-Ulrich
    Siveke, Jens T.
    VIRCHOWS ARCHIV, 2022, 481 (02) : 265 - 272
  • [10] MCL1 Inhibitors in Multiple Myeloma
    Vanderkerken, Karin
    De Veirman, Kim
    Maes, Ken
    Menu, Eline
    De Bruyne, Elke
    BLOOD, 2019, 134
12345