Synthesis, Characterization, and Applications of Zwitterions Containing a Carbanion Moiety

被引：43

作者：

Yanai, Hikaru ^{[1
]}

Yoshino, Tasuku ^{[1
]}

Fujita, Masaya ^{[1
]}

Fukaya, Haruhiko ^{[1
]}

Kotani, Akira ^{[1
]}

Kusu, Fumiyo ^{[1
]}

Taguchi, Takeo ^{[1
]}

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Hachioji, Tokyo 1920392, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 05期

关键词：

aldol reaction; carbanions; homogeneous catalysis; synthetic methodology; zwitterions; MUKAIYAMA-MICHAEL REACTION; EFFICIENT CATALYST; X-RAY; ESTERIFICATION; TRANSESTERIFICATION; ACIDITIES; METHIDE; ACIDS;

D O I：

10.1002/anie.201208809

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A trifle of triflyl: N-substituted anilines react with 1,1,3,3- tetrakis(triflyl)propane to give a 2,2-bis(triflyl)ethyl group at the para position of the ring. The product is a zwitterion with a carbanion and an ammonium moiety, and can be used as an acid catalyst for organic reactions (see scheme). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1560 / 1563

页数：4

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