Activation Pathways of Agonists, Partial Agonists and Inverse Agonist in Beta1 and Beta2 Adrenergic Receptors

被引：0

作者：

Bhattacharya, Supriyo ^{[1
]}

Vaidehi, Nagarajan ^{[1
]}

机构：

[1] City Hope Natl Med Ctr, Beckman Res Inst, Duarte, CA 91010 USA

来源：

BIOPHYSICAL JOURNAL | 2010年 / 98卷 / 03期

关键词：

D O I：

10.1016/j.bpj.2009.12.3543

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

引用

页码：646A / 647A

页数：2

共 3 条

[1] Sequential binding of agonists to the β2 adrenoceptor -: Kinetic evidence for intermediate conformational states [J].

Swaminath, G ;

Xiang, Y ;

Lee, TW ;

Steenhuis, J ;

Parnot, C ;

Kobilka, BK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (01) :686-691

[2] Probing the β2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists [J].

Swaminath, G ;

Deupi, X ;

Lee, TW ;

Zhu, W ;

Thian, FS ;

Kobilka, TS ;

Kobilka, B .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (23) :22165-22171

[3] Structure of a β1-adrenergic G-protein-coupled receptor [J].

Warne, Tony ;

Serrano-Vega, Maria J. ;

Baker, Jillian G. ;

Moukhametzianov, Rouslan ;

Edwards, Patricia C. ;

Henderson, Richard ;

Leslie, Andrew G. W. ;

Tate, Christopher G. ;

Schertler, Gebhard F. X. .

NATURE, 2008, 454 (7203) :486-491

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