Fulminant adenovirus hepatitis after allogeneic bone marrow transplantation

被引：0
|
作者：
Bertheau, P
Parquet, N
Ferchal, F
Gluckman, E
Brocheriou, C
机构：
[1] HOP ST LOUIS,SERV GREFFE MOELLE,F-75010 PARIS,FRANCE
[2] HOP ST LOUIS,MICROBIOL SERV,F-75010 PARIS,FRANCE
[3] ANAT PATHOL LAB,PARIS,FRANCE
来源：
BONE MARROW TRANSPLANTATION | 1996年 / 17卷 / 02期
关键词：
bone marrow transplantation; hepatitis; adenovirus;
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Adenoviruses may cause severe infections in bone marrow transplant recipients. We report the case of a patient who developed fulminant hepatitis 5 months after bone marrow transplantation. Adenovirus type 2 was cultured from stool and blood samples. The patient died from liver failure. Histologic examination of post-mortem liver samples showed extensive necrosis with nuclear inclusions. Adenovirus was identified in liver cells by electron microscopy and immunohistochemical staining using a monoclonal anti-adenovirus antibody. No other pathogen was identified.
引用
收藏
页码：295 / 298
页数：4
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