NMR-based Structural Model of Rabbit Cytochrome P450 2B4 with the Analgesic Amidopyrine, the Intermediate Desmethylamidopyrine, and its Product Aminoantipyrine: Implications for the Structural Basis of Sequential Metabolism

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作者
Roberts, Arthur George [1 ]
Vu, Kathy [2 ]
Halpert, James R. [3 ]
机构
[1] Univ Calif San Diego, Skaggs Sch Pharm, La Jolla, CA 92093 USA
[2] Univ Gothenburg, Sahlgrenska Acad, Gothenburg, Sweden
[3] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA
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Q5 [生物化学]; Q7 [分子生物学];
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071010 ; 081704 ;
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