Neutrophil-lymphocyte and platelet-lymphocyte ratios as inflammation markers for bipolar disorder

被引：102

作者：

Kalelioglu, Tevfik ^{[1
]}

Akkus, Mustafa ^{[1
]}

Karamustafalioglu, Nesrin ^{[2
]}

Genc, Abdullah ^{[1
]}

Genc, Esra Sena ^{[1
]}

Cansiz, Alparslan ^{[1
]}

Emul, Murat ^{[2
]}

机构：

[1] Bakirkoy Mental Hlth Res & Training State Hosp, Dept Psychiat, Istanbul, Turkey

[2] Istanbul Univ, Dept Psychiat, Cerrahpasa Med Sch, Istanbul, Turkey

来源：

PSYCHIATRY RESEARCH | 2015年 / 228卷 / 03期

关键词：

Neutrophil-Lymphocyte Ratio; Platelet-Lymphocyte Ratio; Bipolar Disorder; SCHIZOPHRENIA; CYTOKINES; RECEPTOR; DISEASE;

D O I：

10.1016/j.psychres.2015.05.110

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

In the present study we investigated the involvement of inflammatory cells and their ratios as inflammation markers in Bipolar Disorder. We have enrolled 61 manic, 55 euthymic patients and 54 control subjects to the study. Neutrophil-lymphocyte and platelet-lymphocyte ratios were found significantly higher in both manic and euthymic patients compared to control group. These findings suggest that the inflammatory cells have a role in the pathophysiology of bipolar disorder manic and even in euthymic state. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

引用

页码：925 / 927

页数：3

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