Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: emergence of CTX-M-15-producing E. coli ST131

被引：25

作者：

Kuroda, Hitoshi ^{[1
,2
]}

Yano, Hisakazu ^{[1
]}

Hirakata, Yoichi ^{[3
]}

Arai, Kazuaki ^{[3
]}

Endo, Shiro ^{[1
]}

Kanamori, Hajime ^{[1
]}

Yamamoto, Hiromi ^{[2
]}

Ichimura, Sadahiro ^{[4
]}

Ogawa, Miho ^{[4
]}

Shimojima, Masahiro ^{[4
]}

Komatsu, Mayumi ^{[5
]}

Jonai, Teruko ^{[6
]}

Itagaki, Sachiko ^{[7
]}

Nonomiya, Yuriko ^{[8
]}

Suwabe, Akira ^{[8
]}

Kaku, Mitsuo ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Med, Dept Infect Control & Lab Diagnost, Sendai, Miyagi 9808574, Japan

[2] Taro Clin Miyako City, Dept Internal Med, Miyako, Iwate 0270305, Japan

[3] Tohoku Univ, Grad Sch Med, Dept Clin Microbiol Epidemiol Res & Management &, Sendai, Miyagi 9808574, Japan

[4] BML Inc, Dept Bacteriol, Kawagoe, Saitama 3501101, Japan

[5] Miyagi Med Assoc, Kenko Ctr, Dept Clin Lab, Sendai, Miyagi 9830832, Japan

[6] Iwate Prefectural Miyako Hosp, Dept Clin Lab, Miyako, Iwate 0270096, Japan

[7] Morioka Med Labs, Dept Clin Lab, Morioka, Iwate 0200841, Japan

[8] Iwate Med Univ Hosp, Dept Clin Lab, Morioka, Iwate 0208505, Japan

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2012年 / 74卷 / 02期

关键词：

ESBLs; Escherichia coli; CTX-M-15; PREVALENCE;

D O I：

10.1016/j.diagmicrobio.2012.06.011

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We investigated the molecular characteristics of ESBL-producing Escherichia coli in Japan. A total of 101 clinical isolates of ESBL-positive E. coli collected in Japan between June 2008 and November 2009 were studied. Among the 101 strains, 97 were positive for CTX-M, while 47 and two were positive for TEM and SHV, respectively. Sequencing revealed that CTX-M-14 was most common (49/101). followed by CTX-M-27 (22/101) and CTX-M-15 (8/101). Based on MLST data, seven of eight CTX-M-15 producers belonged to ST131. This is the first report about clinical isolates of E. coli ST131 possessing CTX-M-15 in Japan. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：201 / 203

页数：3

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