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Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: emergence of CTX-M-15-producing E. coli ST131
被引:25
|作者:
Kuroda, Hitoshi
[1
,2
]
Yano, Hisakazu
[1
]
Hirakata, Yoichi
[3
]
Arai, Kazuaki
[3
]
Endo, Shiro
[1
]
Kanamori, Hajime
[1
]
Yamamoto, Hiromi
[2
]
Ichimura, Sadahiro
[4
]
Ogawa, Miho
[4
]
Shimojima, Masahiro
[4
]
Komatsu, Mayumi
[5
]
Jonai, Teruko
[6
]
Itagaki, Sachiko
[7
]
Nonomiya, Yuriko
[8
]
Suwabe, Akira
[8
]
Kaku, Mitsuo
[1
]
机构:
[1] Tohoku Univ, Grad Sch Med, Dept Infect Control & Lab Diagnost, Sendai, Miyagi 9808574, Japan
[2] Taro Clin Miyako City, Dept Internal Med, Miyako, Iwate 0270305, Japan
[3] Tohoku Univ, Grad Sch Med, Dept Clin Microbiol Epidemiol Res & Management &, Sendai, Miyagi 9808574, Japan
[4] BML Inc, Dept Bacteriol, Kawagoe, Saitama 3501101, Japan
[5] Miyagi Med Assoc, Kenko Ctr, Dept Clin Lab, Sendai, Miyagi 9830832, Japan
[6] Iwate Prefectural Miyako Hosp, Dept Clin Lab, Miyako, Iwate 0270096, Japan
[7] Morioka Med Labs, Dept Clin Lab, Morioka, Iwate 0200841, Japan
[8] Iwate Med Univ Hosp, Dept Clin Lab, Morioka, Iwate 0208505, Japan
关键词:
ESBLs;
Escherichia coli;
CTX-M-15;
PREVALENCE;
D O I:
10.1016/j.diagmicrobio.2012.06.011
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
We investigated the molecular characteristics of ESBL-producing Escherichia coli in Japan. A total of 101 clinical isolates of ESBL-positive E. coli collected in Japan between June 2008 and November 2009 were studied. Among the 101 strains, 97 were positive for CTX-M, while 47 and two were positive for TEM and SHV, respectively. Sequencing revealed that CTX-M-14 was most common (49/101). followed by CTX-M-27 (22/101) and CTX-M-15 (8/101). Based on MLST data, seven of eight CTX-M-15 producers belonged to ST131. This is the first report about clinical isolates of E. coli ST131 possessing CTX-M-15 in Japan. (C) 2012 Elsevier Inc. All rights reserved.
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页码:201 / 203
页数:3
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