A convenient synthesis of substituted 2-phenylnaphthalenes from phenylacetones

被引：22
作者：
Cotelle, P
Catteau, JP
机构：
[1] Lab. Chim. Organique Phys. A., ENSCL, Université de Lille 1
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 17期
关键词：
D O I：
10.1016/S0040-4039(97)00531-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of phenylacetones 1 with boron tribromide gives the 1,3-dimethyl-2-phenylnaphtalenes 2 in good yields by a tandem aldol condensation-intramolecular Friedel-Crafts cyclization. In the cases of methoxyphenylacetones, a demethylation occurs leading to 1,3-dimethyl-2-hydroxyphenylnaphtols. (C) 1997 Published by Elsevier Science Ltd.
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页码：2969 / 2972
页数：4
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