High Prevalence of Ancylostoma ceylanicum Hookworm Infections in Humans, Cambodia, 2012

被引：115

作者：

Inpankaew, Tawin ^{[1
,2
]}

Schaer, Fabian ^{[3
,4
]}

Dalsgaard, Anders ^{[1
]}

Khieu, Virak ^{[3
,4
,5
]}

Chimnoi, Wissanuwat ^{[2
]}

Chhoun, Chamnan ^{[6
]}

Sok, Daream ^{[6
]}

Marti, Hanspeter ^{[3
,4
]}

Muth, Sinuon ^{[5
]}

Odermatt, Peter ^{[3
,4
]}

Traub, Rebecca J. ^{[7
,8
]}

机构：

[1] Univ Copenhagen, Copenhagen, Denmark

[2] Kasetsart Univ, Bangkok, Thailand

[3] Swiss Trop & Publ Hlth Inst, Basel, Switzerland

[4] Univ Basel, Basel, Switzerland

[5] Natl Ctr Parasitol Entomol & Malaria Control, Phnom Penh, Cambodia

[6] Fisheries Adm, Phnom Penh, Cambodia

[7] Univ Queensland, Gatton, Qld, Australia

[8] Univ Melbourne, Parkville, Vic 3052, Australia

来源：

EMERGING INFECTIOUS DISEASES | 2014年 / 20卷 / 06期

关键词：

DOGS; PCR; INFESTATION; BRAZILIENSE; AUSTRALIA; COMMUNITY; NEMATODE; TOOLS; CATS; LAOS;

D O I：

10.3201/eid2006.131770

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and risk factors for hookworm infections in humans and dogs in a rural Cambodian village. Over 57% of the population was infected with hookworms; of those, 52% harbored A. ceylanicum hookworms. The greatest intensities of A. ceylanicum eggs were in persons 21-30 years of age. Over 90% of dogs also harbored A. ceylanicum hookworms. Characterization of the cytochrome oxidase-1 gene divided isolates of A. ceylanicum hookworms into 2 groups, 1 containing isolates from humans only and the other a mix of isolates from humans and animals. We hypothesize that preventative chemotherapy in the absence of concurrent hygiene and animal health programs may be a factor leading to emergence of A. ceylanicum infections; thus, we advocate for a One Health approach to control this zoonosis.

引用

页码：976 / 982

页数：7

共 34 条

[1] ANTEN J F, 1964, Ned Tijdschr Geneeskd, V108, P1664
[2] ANTEN J. F. G., 1964, TROP GEOGR MED, V16, P216
[3] Expression of acquired immunity to the hookworm Ancylostoma ceylanicum in hamsters
Behnke, JM
Guest, J
Rose, R
[J]. PARASITE IMMUNOLOGY, 1997, 19 (07) : 309 - 318
[4] Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
Bethony, J
Brooker, S
Albonico, M
Geiger, SM
Loukas, A
Diemert, D
Hotez, PJ
[J]. LANCET, 2006, 367 (9521) : 1521 - 1532
[5] CARROLL SM, 1986, TROP GEOGR MED, V38, P38
[6] ANCYLOSTOMA-CEYLANICUM - PARASITE OF MAN IN CALCUTTA AND ENVIRONS
CHOWDHURY, AB
SCHAD, GA
[J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1972, 21 (03) : 300 - +
[7] Diagnosis of Ancylostoma ceylanicum infestation by single-balloon enteroscopy
Chung, Chen-Shuan
Lin, Cheng-Kuan
Su, Kua-Eyre
Liu, Chia-Ying
Lin, Chien-Chu
Liang, Cheng-Chao
Lee, Tzong-Hsi
[J]. GASTROINTESTINAL ENDOSCOPY, 2012, 76 (03) : 671 - 672
[8] Soil-Transmitted Helminthiasis in Laos: A Community-Wide Cross-Sectional Study of Humans and Dogs in a Mass Drug Administration Environment
Conlan, James V.
Khamlome, Boualam
Vongxay, Khamphouth
Elliot, Aileen
Pallant, Louise
Sripa, Banchob
Blacksell, Stuart D.
Fenwick, Stanley
Thompson, R. C. Andrew
[J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2012, 86 (04) : 624 - 634
[9] Intestinal allergy expels hookworms: seeing is believing
Croese, John
Speare, Richard
[J]. TRENDS IN PARASITOLOGY, 2006, 22 (12) : 547 - 550
[10] The public health importance of hookworm disease
Crompton, DWT
[J]. PARASITOLOGY, 2000, 121 : S39 - S50

← 1 2 3 4 →