Pancreatic injuries in earthquake victims: What have we learnt?

被引:5
|
作者
Xie, Kun-Lin [1 ]
Liu, Jun [2 ]
Pan, Gang [1 ]
Hu, Wei-Ming [1 ]
Wan, Mei-Hua [3 ]
Tang, Wen-Fu [3 ]
Liu, Xu-Bao [1 ]
Wu, Hong [1 ]
机构
[1] Sichuan Univ, West China Hosp, Dept Hepatobiliary Pancreato Surg, Chengdu 610041, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp, Dept Pharm, Chengdu 610041, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp, Dept Integrated Tradit & Western Med, Chengdu 610041, Sichuan, Peoples R China
关键词
Pancreas; Injury; Earthquake; SERUM AMYLASE; TRAUMA; MANAGEMENT; DIAGNOSIS; PREDICTORS; OUTCOMES; LIPASE; GRADE;
D O I
10.1016/j.pan.2013.10.002
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objective: To analyze the clinical characteristic and management of patients with pancreatic injuries from the Wen-Chuan and Lu-Shan earthquakes. Methods: We retrospectively reviewed 39,784 patients from the Wen-Chuan earthquake and 1489 from the Lu-Shan earthquake. The demographics, clinical data, treatment strategies, and outcomes of patients with pancreatic injuries were recorded and compared between survivors of the two earthquakes. Results: Pancreatic injury occurred only in a small proportion (0.2%) in patients with trauma on admission, and most (61%) patients had Grades I-II pancreatic injuries. Blunt trauma was the leading cause of pancreatic trauma. Most patients (95%) suffered multiple injuries, of which chest injuries (61%) were the most common. Elevated serum amylase levels were observed in 50 (86%) of 58 patients, and computed tomography (CT) identified pancreatic injuries in 32(80%) of 40 patients. A significantly higher rate (p = 0.043) of pancreatic complication was present in patients with Grade III and IV injuries (38%) than in those with Grade I and II injuries (18%). Forty patients were initially treated by conservative management with 6 (15%) requiring delayed operations. Four (67%) pancreatic complications and 2 (33%) deaths occurred in patients with delayed operations. Conclusions: Repeated serum amylase analysis, CT, and laparoscopic exploration were reliable diagnostic modalities to diagnose pancreatic injury. Conservative management was safe in patients with Grade I and II injuries. Delayed operation, especially for Grade III patients, resulted in increased morbidity and mortality. Copyright (C) 2013, IAP and EPC. Published by Elsevier India, a division of Reed Elsevier India Pvt. Ltd. All rights reserved.
引用
收藏
页码:605 / 609
页数:5
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