Screening mammography-detected ductal carcinoma in situ: mammographic features based on breast cancer subtypes

被引:21
作者
Kim, Mi Young [1 ]
Kim, Hyeon Sook [2 ]
Choi, Nami [1 ]
Yang, Jung-Hyun [3 ]
Yoo, Young Bum [3 ]
Park, Kyoung Sik [3 ]
机构
[1] Konkuk Univ, Sch Med, Med Ctr, Dept Radiol, Seoul, South Korea
[2] Catholic Univ Korea, St Pauls Hosp, Dept Radiol, Seoul, South Korea
[3] Konkuk Univ, Sch Med, Med Ctr, Dept Surg, Seoul, South Korea
关键词
Breast; Mammography; Calcification; ER; HER2; SURGICAL ADJUVANT BREAST; INTRADUCTAL-CARCINOMA; PATHOLOGICAL FINDINGS; CONSERVING THERAPY; ESTROGEN-RECEPTOR; RISK-FACTORS; RECURRENCE; EVENTS; UPDATE; TRIAL;
D O I
10.1016/j.clinimag.2015.06.006
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We evaluated the mammographic and histopathologic features of screening mammography-detected ductal carcinoma in situ (DCIS) based on the breast cancer subtypes determined by immunohistochemistry. A total of 94 patients with 94 screening mammography-detected DCIS were included in this study. Mammographically, human epidermal growth factor receptor 2 (HER2)-positive DCIS was more commonly associated with calcifications than estrogen receptor (ER)-positive and triple-negative DCIS (P=.003). Histopathologically, HER2-positive DCIS and triple-negative DCIS were associated with high nuclear grade (P <=.001) and comedo necrosis (P <=.001) than ER-positive DCIS. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:983 / 986
页数:4
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