Long-term quality of life of liver transplant recipients beyond 60 years of age

被引:13
作者
Werkgartner, G. [1 ]
Wagner, D. [2 ]
Manhal, S. [3 ]
Fahrleitner-Pammer, A. [4 ]
Mischinger, H. J. [1 ]
Wagner, M. [4 ]
Grgic, R. [2 ]
Roller, R. E. [5 ]
Kniepeiss, D. [2 ]
机构
[1] Med Univ Graz, Dept Surg, Div Gen Surg, A-8036 Graz, Austria
[2] Med Univ Graz, Dept Surg, Div Transplantat, A-8036 Graz, Austria
[3] Med Univ Graz, Off Vice Rector Studies & Teaching, A-8036 Graz, Austria
[4] Med Univ Graz, Dept Internal Med, Div Endocrinol & Metab, A-8036 Graz, Austria
[5] Med Univ Graz, Dept Internal Med, Div Geriatr, A-8036 Graz, Austria
关键词
Liver transplantation; Immunosuppression; Quality of life; SF-36; OLDER;
D O I
10.1007/s11357-013-9527-x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Due to ameliorated surgery as well as better immunosuppression, the recipient age after liver transplantation has been extended over the past years. This study aimed to investigate the health related quality of life after liver transplantation in recipients beyond 60 years of age. The SF-36 was used to evaluate the recipients' health-related quality of life as standardized tool. It comprises 36 items that are attributed to 8 subscales attributed to 2 components: the physical component score and the mental component score. Differences in the health-related quality of life between the included aged recipients and age-matched general population as well as among female and male recipients. Aged recipients showed significantly lower scores in physical functioning (29 vs. 76, p = 0.001), role physical (42 vs. 73, p = 0.003), bodily pain (34 vs. 71, p = 0.003), general health (28 vs. 59, p = 0.001), vitality (25 vs. 61, p = 0.001), social functioning (36 vs. 87, p = 0.001), role emotional (46 vs. 89, p = 0.001) as well as the physical component score (28 vs. 76, p = 0.001). Aged female recipients showed lower results as compared to males in social functioning, physical functioning, role physical, and social functioning (p = 0.03 respectively) but comparable results in the remaining. Quality of life seems to be an issue among aged recipients and should be assessed on a regular basis.
引用
收藏
页码:2485 / 2492
页数:8
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