Polythiophenes in Biological Applications

被引:37
作者
Sista, Prakash [1 ]
Ghosh, Koushik [1 ]
Martinez, Jennifer S. [1 ]
Rocha, Reginaldo C. [1 ]
机构
[1] Los Alamos Natl Lab, MPA CINT, Los Alamos, NM 87545 USA
关键词
Polythiophenes; Applications; Diagnostics; Therapy; Drug Delivery; Imaging; Implant Devices; Artificial Organs; HEAD-TO-TAIL; CATALYST-TRANSFER POLYCONDENSATION; CONDUCTING-POLYMER NANOTUBES; CHAIN-GROWTH POLYMERIZATION; ACCEPTOR SEMICONDUCTING POLYMERS; ACTIVATED BIOCIDAL ACTIVITY; CROSS-COUPLING REACTION; CONJUGATED POLYMERS; REGIOREGULAR POLY(3-HEXYLTHIOPHENE); OPTOELECTRONIC PROPERTIES;
D O I
10.1166/jnn.2014.9111
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Polythiophene and its derivatives have shown tremendous potential for interfacing electrically conducting polymers with biological applications. These semiconducting organic polymers are relatively soft, conduct electrons and ions, have low cytotoxicity, and can undergo facile chemical modifications. In addition, the reduction in electrical impedance of electrodes coated with polythiophenes may prove to be invaluable for a stable and permanent connection between devices and biological tissues. This review article focuses on the synthesis and some key applications of polythiophenes in multidisciplinary areas at the interface with biology. These polymers have shown tremendous potential in biological applications such as diagnostics, therapy, drug delivery, imaging, implant devices and artificial organs.
引用
收藏
页码:250 / 272
页数:23
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