Stoichiometry of lipid-protein interaction and integral membrane protein structure

被引：57
作者：
Marsh, D
机构：
[1] Max-Planck-Inst. Biophysik. Chem., Abteilung Spektroskopie, D-37077 Göttingen, Am Fassberg
来源：
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS | 1997年 / 26卷 / 02期
关键词：
D O I：
10.1007/s002490050072
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
The stoichiometries of lipid-protein interaction obtained from spin label electron spin resonance experiments with integral membrane proteins are compared with simple geometric models for the intramembranous perimeter that are based on the predicted numbers of transmembrane helices. Deviations from the predicted values provide evidence for oligomerization of the protein in the membrane and/or more complex arrangements of the transmembrane segments.
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页码：203 / 208
页数：6
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