In situ fluoride retention and remineralization of incipient carious lesions after the application of different concentrations of fluoride

被引:11
作者
Altenburger, Markus J. [1 ,2 ]
Schirrmeister, Joerg F. [1 ,2 ]
Lussi, Adrian [3 ]
Klasser, Manfred [4 ]
Hellwig, Elmar [1 ,2 ]
机构
[1] Univ Freiburg, Univ Hosp, Dept Operat Dent & Periodontol, Freiburg, Germany
[2] Univ Freiburg, Sch Dent, Freiburg, Germany
[3] Univ Bern, Sch Dent Med, Dept Prevent Restorat & Pediat Dent, Bern, Switzerland
[4] GWD Consult, Mulheim, Germany
关键词
enamel; fluoride retention; in situ; remineralization; ENAMEL LESIONS; MODEL; GEL;
D O I
10.1111/j.1600-0722.2008.00585.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Limited information is available on the time-dependent or dosage-dependent cariostatic efficacy of highly concentrated fluoride compounds. This good clinical practice-conforming, double-blind, placebo-controlled, crossover in situ study tested the hypothesis that a 1.0% amine fluoride fluid is superior to a 0.5% amine fluoride fluid regarding fluoride retention and mineral change in initial caries enamel lesions over a period of 28 d. Fluoride retention was significantly higher after application of the two fluoride fluids compared with placebo but had decreased in both groups to similar levels after only 1 wk. Mineral gain was significantly higher for both verum groups compared with placebo. The use of 1% fluoride fluid resulted in significantly higher remineralization compared with the use of 0.5% fluoride fluid. For both fluoride fluids mineral gain followed a linear relationship with time during the experimental period, indicating a possible further uptake of mineral, even after 4 wk.
引用
收藏
页码:58 / 63
页数:6
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