Prescription opioid use among older adults with arthritis or low back pain

被引:50
作者
Solomon, DH [1 ]
Avorn, J [1 ]
Wang, PS [1 ]
Vaillant, G [1 ]
Cabral, D [1 ]
Mogun, H [1 ]
Stürmer, T [1 ]
机构
[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Boston, MA 02115 USA
来源
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH | 2006年 / 55卷 / 01期
关键词
opioid analgesics; prescription patterns; health services use; rheumatoid arthritis; osteoarthritis; low back pain;
D O I
10.1002/art.21697
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective. To examine patterns of chronic opioid use in selected groups with arthritis and low back pain and compare them with patterns among persons with ischemic heart disease. Methods. The study database consisted of Medicare beneficiaries who were enrolled in a drug benefit program for low-to-moderate income Pennsylvania residents. We identified selected patients who had a diagnosis of rheumatoid arthritis, osteoarthritis, chronic low back pain, or ischemic heart disease since 1995. Chronic opioid use, defined as at least six 30-day prescriptions in a year, was the endpoint of interest. We examined the proportion of patients meeting this definition during the period 1996-2001 and determined predictors based on multivariable Cox proportional hazards models. Results. Four percent of subjects with rheumatoid arthritis used opioids chronically in 2001, compared with < 1% in each of the other groups. There was no increase in the chronic use of opioids over the 6-year study period. Low-potency opioids were the most commonly prescribed preparations for chronic users from all patient groups. The prior use of medicines for psychiatric illness, including benzodiazepines or barbiturates, was associated with chronic prescription opioid use across all diagnoses. However, subjects with a prior diagnosis of psychiatric illness were less likely to receive chronic opioids. Conclusion. Chronic opioid use is relatively uncommon, even among older individuals with arthritis or low back pain. The proportion of these individuals receiving such medicines has not increased in the late 1990s. There seems to be a complex relationship between psychiatric medication use, psychiatric diagnoses, and the use of chronic opioids among these individuals.
引用
收藏
页码:35 / 41
页数:7
相关论文
共 16 条
[1]  
Altman RD, 2000, ARTHRITIS RHEUM-US, V43, P1905
[2]  
*AM PAIN SOC, PROM PAIN REL PREV A
[3]  
[Anonymous], 1996, Goodman Gilman's the pharmacological basis of therapeutics
[4]  
*ARTHR PAIN GUID P, 2002, GUID MAN PAIN OST RH
[5]   Office visits and analgesic prescriptions for musculoskeletal pain in US: 1980 vs. 2000 [J].
Caudill-Slosberg, MA ;
Schwartz, LM ;
Woloshin, S .
PAIN, 2004, 109 (03) :514-519
[6]  
*CDCP, 2000, HLTH PEOPL 2010
[7]   ADAPTING A CLINICAL COMORBIDITY INDEX FOR USE WITH ICD-9-CM ADMINISTRATIVE DATABASES [J].
DEYO, RA ;
CHERKIN, DC ;
CIOL, MA .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1992, 45 (06) :613-619
[8]  
Gonzales G R, 1993, Arthritis Care Res, V6, P223, DOI 10.1002/art.1790060409
[9]   Characterizations of long-term oxycodone/acetaminophen prescriptions in veteran patients [J].
Hermos, JA ;
Young, MM ;
Gagnon, DR ;
Fiore, LD .
ARCHIVES OF INTERNAL MEDICINE, 2004, 164 (21) :2361-2366
[10]  
Lawrence RC, 1998, ARTHRITIS RHEUM-US, V41, P778, DOI 10.1002/1529-0131(199805)41:5<778::AID-ART4>3.0.CO