Metabonomic approaches to nutrient metabolism and future molecular nutrition

被引：14

作者：

Rezzi, Serge ^{[1
]}

Collino, Sebastian ^{[1
]}

Goulet, Laurence ^{[1
]}

Martin, Francois-Pierre ^{[1
]}

机构：

[1] Nestle Inst Hlth Sci SA, CH-1015 Lausanne, Switzerland

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2013年 / 52卷

关键词：

Biomarker; Metabonomics; Metabolomics; Micronutrient; Nutrient; Nutritional phenotype; Omics; Stratified nutrient requirements; System biology; Targeted nutrition; FATTY-LIVER-DISEASE; ALZHEIMER-DISEASE; PLATELET ACTIVATION; SYSTEMS BIOLOGY; GUT MICROBIOTA; METABOLOMICS; OBESE; DIET; RISK; NMR;

D O I：

10.1016/j.trac.2013.09.004

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Metabonomics provides access to the environmental, diet, genetic and metagenetic integrative metabolic phenotype of individuals. Recent advances in spectroscopic and chromatographic techniques can capture metabolites and nutrients within a broad dynamic range. Applications to nutrition sciences have addressed nutrient metabolism and diet-related phenotypes under healthy and pathological conditions. Future molecular stratified nutrition requires development of comprehensive, quantitative profiling of nutrients to match the individual's specific requirements and metabolic peculiarities (metabolic phenotype) to improve health and dietary management of medical conditions. (c) 2013 Elsevier Ltd. All rights reserved.

引用

页码：112 / 119

页数：8

共 70 条

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