Electrolyzed-Reduced Water: Review II: Safety Concerns and Effectiveness as a Source of Hydrogen Water

被引:7
作者
LeBaron, Tyler W. [1 ,2 ,3 ]
Sharpe, Randy [4 ]
Ohno, Kinji [5 ]
机构
[1] Slovak Acad Sci, Inst Heart Res, Ctr Expt Med, Bratislava 84104, Slovakia
[2] Mol Hydrogen Inst, Enoch, UT 84721 USA
[3] Southern Utah Univ, Dept Kinesiol & Outdoor Recreat, Cedar City, UT 84720 USA
[4] H2 Analyt, Henderson, NV 89052 USA
[5] Nagoya Univ, Ctr Neurol Dis & Canc, Div Neurogenet, Grad Sch Med, Nagoya 4668550, Japan
关键词
electrolyzed reduced water; alkaline ionized water; high pH water; safety of ERW; water ionizer; molecular hydrogen; oxidation-reduction potential; electrolyzed oxidizing water; PROTON PUMP INHIBITORS; PLATINUM NANOPARTICLES; GUT MICROBIOTA; RICH WATER; IN-VITRO; DAMAGE; RATS; HEALTH; IMPACT; GAS;
D O I
10.3390/ijms232314508
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many studies demonstrate the safety of alkaline-electrolyzed-reduced water (ERW); however, several animal studies have reported significant tissue damage and hyperkalemia after drinking ERW. The mechanism responsible for these results remains unknown but may be due to electrode degradation associated with the production of higher pH, in which platinum nanoparticles and other metals that have harmful effects may leach into the water. Clinical studies have reported that, when ERW exceeds pH 9.8, some people develop dangerous hyperkalemia. Accordingly, regulations on ERW mandate that the pH of ERW should not exceed 9.8. It is recommended that those with impaired kidney function refrain from using ERW without medical supervision. Other potential safety concerns include impaired growth, reduced mineral, vitamin, and nutrient absorption, harmful bacterial overgrowth, and damage to the mucosal lining causing excessive thirst. Since the concentration of H-2 in ERW may be well below therapeutic levels, users are encouraged to frequently measure the H-2 concentration with accurate methods, avoiding ORP or ORP-based H-2 meters. Importantly, although, there have been many people that have used high-pH ERW without any issues, additional safety research on ERW is warranted, and ERW users should follow recommendations to not ingest ERW above 9.8 pH.
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页数:14
相关论文
共 75 条
  • [1] Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level
    Abe, Masumi
    Sato, Shunpei
    Toh, Kazuko
    Hamasaki, Takeki
    Nakamichi, Noboru
    Teruya, Kiichiro
    Katakura, Yoshinori
    Morisawa, Shinkatsu
    Shirahata, Sanetaka
    [J]. ANIMAL CELL TECHNOLOGY: BASICS & APPLIED ASPECTS, 2010, 16 : 315 - 321
  • [2] Baking Soda Can Settle the Stomach but Upset the Heart: Case Files of the Medical Toxicology Fellowship at the University of California, San Francisco
    Al-Abri S.A.
    Olson K.R.
    [J]. Journal of Medical Toxicology, 2013, 9 (3) : 255 - 258
  • [3] Use of redox potential modification by gas improves microbial quality, color retention, and ascorbic acid stability of pasteurized orange juice
    Alwazeer, D
    Delbeau, C
    Divies, C
    Cachon, R
    [J]. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2003, 89 (01) : 21 - 29
  • [4] DNA damage and p53-mediated growth arrest in human cells treated with platinum nanoparticles
    Asharani, P. V.
    Xinyi, Ng
    Hande, M. Prakash
    Valiyaveettil, Suresh
    [J]. NANOMEDICINE, 2010, 5 (01) : 51 - 64
  • [5] Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems
    Barancik, Miroslav
    Kura, Branislav
    LeBaron, Tyler W.
    Bolli, Roberto
    Buday, Jozef
    Slezak, Jan
    [J]. ANTIOXIDANTS, 2020, 9 (12) : 1 - 21
  • [6] Bodner M, 2018, Fuel Cells and Hydrogen: From Fundamentals to Applied Research, P139, DOI 10.1016/B978-0-12-811459-9.00007-4
  • [7] Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson's disease
    Bordoni, Laura
    Gabbianelli, Rosita
    Fedeli, Donatella
    Fiorini, Dennis
    Bergheim, Ina
    Jin, Cheng Jun
    Marinelli, Lisa
    Di Stefano, Antonio
    Nasuti, Cinzia
    [J]. PLOS ONE, 2019, 14 (10):
  • [8] Electrolyzed Water and Its Pharmacological Activities: A Mini-Review
    Chen, Bo-Kai
    Wang, Chin-Kun
    [J]. MOLECULES, 2022, 27 (04):
  • [9] Neuroprotective Effects of Molecular Hydrogen: A Critical Review
    Chen, Wei
    Zhang, Han-Ting
    Qin, Shu-Cun
    [J]. NEUROSCIENCE BULLETIN, 2021, 37 (03) : 389 - 404
  • [10] Enagic I., 2013, ENAGIC LEVELUK PRODU