Rh(III)-catalyzed chelation-assisted intermolecular carbenoid functionalization of α-imino Csp3-H bonds

被引：43
作者：
Chen, Xun [1 ]
Xie, Ying [1 ]
Xiao, Xinsheng [1 ]
Li, Guoqiang [2 ]
Deng, Yuanfu [1 ]
Jiang, Huanfeng [1 ]
Zeng, Wei [1 ]
机构：
[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510641, Guangdong, Peoples R China
[2] Jinan Univ, Anal & Testing Ctr, Guangzhou 510632, Guangdong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 83期
关键词：
C-H FUNCTIONALIZATION; INSERTION REACTIONS; ONE-POT; CYCLIZATION; ALKYNES; CYCLOPROPANATION; DIAZOOXINDOLES; KETOIMINES; ALDEHYDES; ACCESS;
D O I：
10.1039/c5cc06428g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Rh(III)-catalyzed cross-coupling/cyclization cascade of alpha-imino Csp(3)-H bonds with donor/acceptor alpha-acyl diazocarbonyl compounds has been developed. This novel transformation involves ligand-directed Csp(3)-H bond functionalization with carbenoids under the pyridine-chelation assistance, and offered an efficient access to synthetically versatile polysubstituted N-(2-pyridyl)pyrroles with a broad range of functional group tolerance.
引用
收藏
页码：15328 / 15331
页数：4
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