Single-molecule fluorescence near a metal layer

被引：97

作者：

Enderlein, J ^{[1
]}

机构：

[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-93040 Regensburg, Germany

来源：

CHEMICAL PHYSICS | 1999年 / 247卷 / 01期

关键词：

D O I：

10.1016/S0301-0104(99)00097-X

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A theoretical study of the fluorescence emission properties of a single dye molecule near a metal film is presented. The study accounts not only for the well-known fluorescing quenching of a dye near a metal interface, but also for the reduced photobleaching rate due to the enhanced de-excitation rate. it is shown, that despite the high fluorescence quenching rates, the increased photostability of the molecule makes spectroscopic studies on single-molecule level feasible. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：1 / 9

页数：9

共 24 条

[1] SINGLE-MOLECULE DETECTION AND PHOTOCHEMISTRY ON A SURFACE USING NEAR-FIELD OPTICAL-EXCITATION [J].

AMBROSE, WP ;

GOODWIN, PM ;

MARTIN, JC ;

KELLER, RA .

PHYSICAL REVIEW LETTERS, 1994, 72 (01) :160-163

[2]

[Anonymous], 1974, PROGR OPTICS

[3]

BRORSON SD, 1995, SPONTANEOUS EMISSION, P151

[4]

Chance R.R., 1978, ADV CHEM PHYS, P1

[5] On/off blinking and switching behaviour of single molecules of green fluorescent protein [J].

Dickson, RM ;

Cubitt, AB ;

Tsien, RY ;

Moerner, WE .

NATURE, 1997, 388 (6640) :355-358

[6] Highly efficient optical detection of surface-generated fluorescence [J].

Enderlein, J ;

Ruckstuhl, T ;

Seeger, S .

APPLIED OPTICS, 1999, 38 (04) :724-732

[7] Quantum jumps of single molecules at room temperature [J].

Ha, T ;

Enderle, T ;

Chemla, DS ;

Selvin, PR ;

Weiss, S .

CHEMICAL PHYSICS LETTERS, 1997, 271 (1-3) :1-5

[8] Hindered rotational diffusion and rotational jumps of single molecules [J].

Ha, T ;

Glass, J ;

Enderle, T ;

Chemla, DS ;

Weiss, S .

PHYSICAL REVIEW LETTERS, 1998, 80 (10) :2093-2096

[9] Single molecule dynamics studied by polarization modulation [J].

Ha, T ;

Enderle, T ;

Chemla, DS ;

Selvin, PR ;

Weiss, S .

PHYSICAL REVIEW LETTERS, 1996, 77 (19) :3979-3982

[10] QUANTUM EFFICIENCY INDEPENDENCE OF TIME INTEGRATED EMISSION FROM A FLUORESCENT MOLECULE [J].

HIRSCHFELD, T .

APPLIED OPTICS, 1976, 15 (12) :3135-3139

← 1 2 3 →